Iran is a developing country facing demographic transition. Cancers are among the major
non-communicable disorders with remarkable budern on the health-care governing …

Background: Pancreatic cancer can be a very debilitating disease. In the USA and around
the world, pancreatic cancer is among the causes of cancer-related deaths. This study aims …

Background Sequential nab-paclitaxel plus gemcitabine followed by modified FOLFOX-6
(oxaliplatin, leucovorin, and 5-fluorouracil)(nab-P/Gem-mFOLFOX) showed a good safety …

Abstract Background National Comprehensive Cancer Network (NCCN) recently
recommended germline genetic testing for all pancreatic cancer patients. However, the …

Liposomal irinotecan (nal-IRI; Onivyde®; also known as pegylated liposomal irinotecan) has
been developed with the aim of maximising anti-tumour efficacy while minimising drug …

Drug combination therapies for cancer treatment show high efficacy but often induce severe
side effects, resulting in dose or cycle number reduction. We investigated the impact of …

Background The epigenetic mechanisms involved in the progression of pancreatic ductal
adenocarcinoma (PDAC) remain largely unexplored. This study aimed to identify key …

Pancreatic ductal adenocarcinoma (PDAC) is the seventh leading cause of cancer death
worldwide; most of cases are sporadic, however about 5% to 10% report a hereditary …

The association between non-alcoholic fatty liver disease (NAFLD) and the risk of pancreatic
cancer in the general population remains unclear. This nationwide cohort study included …

Pancreatic cancer (PC) and biliary tract cancer (BTC) are both aggressive and highly fatal
malignancies. Nowadays we have a profound knowledge about the molecular landscape of …