Aggregation-induced emission photosensitizer-based photodynamic therapy in cancer: from chemical to clinical

Z Meng, H Xue, T Wang, B Chen, X Dong… - Journal of …, 2022 - Springer
Cancer remains a serious threat to human health owing to the lack of effective treatments.
Photodynamic therapy (PDT) has emerged as a promising non-invasive cancer treatment …

Aggregation‐induced emission luminogens for in vivo molecular imaging and theranostics in cancer

P Cen, J Huang, C Jin, J Wang, Y Wei, H Zhang… - …, 2023 - Wiley Online Library
Cancer is one of the most fatal diseases for decades. Aggregation‐induced emission
luminogens (AIEgens) have been recently used as molecular imaging or therapeutic agents …

Biomimetic doxorubicin/ginsenoside co-loading nanosystem for chemoimmunotherapy of acute myeloid leukemia

M Chen, Y Qiao, J Cao, L Ta, T Ci, X Ke - Journal of Nanobiotechnology, 2022 - Springer
Background Acute myeloid leukemia (AML) showed limited clinical therapeutic efficiency
with chemotherapy for its multi-distributed lesions and hard-to-kill leukemia cells deep in the …

Nanomedicine‐boosting icaritin-based immunotherapy of advanced hepatocellular carcinoma

Y Lu, Y Gao, H Yang, Y Hu, X Li - Military Medical Research, 2022 - Springer
Traditional treatments for advanced hepatocellular carcinoma (HCC), such as surgical
resection, transplantation, radiofrequency ablation, and chemotherapy are unsatisfactory …

Construction of intelligent drug delivery system based on polysaccharide-derived polymer micelles: A review

H Xue, Y Ju, X Ye, M Dai, C Tang, L Liu - International Journal of Biological …, 2023 - Elsevier
Micelles are nanostructures developed via the spontaneous assembly of amphiphilic
polymers in aqueous systems, which possess the advantages of high drug stability or active …

Reactive oxygen nano-generators for cancer therapy

D Kalyane, D Choudhary, S Polaka, H Goykar… - Progress in Materials …, 2022 - Elsevier
Reactive oxygen species (ROS) play a vital role in the biological process. Interestingly,
based on the concentration of the ROS level, they can be beneficial or detrimental to tumor …

Recent Advances in Reprogramming Strategy of Tumor Microenvironment for Rejuvenating Photosensitizers‐Mediated Photodynamic Therapy

Q Yu, X Li, J Wang, L Guo, L Huang, W Gao - Small, 2024 - Wiley Online Library
Photodynamic therapy (PDT) has recently been considered a potential tumor therapy due to
its time‐space specificity and non‐invasive advantages. PDT can not only directly kill tumor …

CRISPR/Cas9-based application for cancer therapy: challenges and solutions for non-viral delivery

YQ Lin, KK Feng, JY Lu, JQ Le, WL Li, BC Zhang… - Journal of Controlled …, 2023 - Elsevier
CRISPR/Cas9 genome editing is a promising therapeutic technique, which makes precise
and rapid gene editing technology possible on account of its high sensitivity and efficiency …

[HTML][HTML] Biotin receptor and mitochondria dual targeted AIE photosensitizer for fluorescence imaging guided photodynamic anticancer therapy

L Pan, S Wang, M Xie, M Liang, L Yu, B Du, X Ye… - Materials & Design, 2023 - Elsevier
Rational design of organelle targeted therapeutic platform in where the drug can be targeted
to destroy tumor cells as much as possible, is one of the effective ways to improve the …

Advantages of combined photodynamic therapy in the treatment of oncological diseases

M Grin, N Suvorov, P Ostroverkhov, V Pogorilyy… - Biophysical …, 2022 - Springer
When conducting combined therapy of malignant neoplasms, treatment methods with
various mechanisms of antitumor effects are used, while an additive or even synergistic …