Lipid polymer hybrid nanoparticles: a custom-tailored next-generation approach for cancer therapeutics

KR Gajbhiye, R Salve, M Narwade, A Sheikh… - Molecular Cancer, 2023 - Springer
Lipid-based polymeric nanoparticles are the highly popular carrier systems for cancer drug
therapy. But presently, detailed investigations have revealed their flaws as drug delivery …

Folic acid functionalized nanoparticles as pharmaceutical carriers in drug delivery systems

A Narmani, M Rezvani, B Farhood… - Drug development …, 2019 - Wiley Online Library
Conventional chemotherapeutic approaches in cancer therapy such as surgery,
chemotherapy, and radiotherapy have several disadvantages due to their nontargeted …

A review of the structure, preparation, and application of NLCs, PNPs, and PLNs

Q Li, T Cai, Y Huang, X Xia, SPC Cole, Y Cai - Nanomaterials, 2017 - mdpi.com
Nanostructured lipid carriers (NLCs) are modified solid lipid nanoparticles (SLNs) that retain
the characteristics of the SLN, improve drug stability and loading capacity, and prevent drug …

[HTML][HTML] Lipid polymer hybrid nanocarriers: Insights into synthesis aspects, characterization, release mechanisms, surface functionalization and potential implications

S Shah, P Famta, RS Raghuvanshi, SB Singh… - Colloid and Interface …, 2022 - Elsevier
Lipid polymer hybrid nanoparticles (LPHN) are novel systems which are potentially
emerging in the era of nano-medicine. They are core-shell nanostructures which comprise of …

Injectable thermosensitive hydrogel containing erlotinib‐loaded hollow mesoporous silica nanoparticles as a localized drug delivery system for NSCLC therapy

X Zhou, X He, K Shi, L Yuan, Y Yang, Q Liu… - Advanced …, 2020 - Wiley Online Library
Erlotinib (ERT), oral administration agents, is one of the most pivotal targeted drugs in the
treatment of non‐small cell lung cancer (NSCLC); however, its poor solubility, low oral …

Beyond liposomes: Recent advances on lipid based nanostructures for poorly soluble/poorly permeable drug delivery

MC Teixeira, C Carbone, EB Souto - Progress in lipid research, 2017 - Elsevier
Solid lipid nanoparticle (SLN), nanostructured lipid carriers (NLC) and hybrid nanoparticles,
have gained increasing interest as drug delivery systems because of their potential to load …

New insights into designing hybrid nanoparticles for lung cancer: Diagnosis and treatment

F Mottaghitalab, M Farokhi, Y Fatahi, F Atyabi… - Journal of controlled …, 2019 - Elsevier
Lung cancer is the foremost reason of death from cancers with broad genetic and epigenetic
diversity. Various strategies are clinically available for diagnosis and treatment of lung …

Poly-ε-caprolactone (PCL), a promising polymer for pharmaceutical and biomedical applications: Focus on nanomedicine in cancer

SM Espinoza, HI Patil… - … Journal of Polymeric …, 2020 - Taylor & Francis
Abstract Poly-ε-caprolactone (PCL) has been the subject of extensive research in the past
few years. It is widely explored in drug delivery, where the development of nanomedicines …

Biomimetics in drug delivery systems: A critical review

M Sheikhpour, L Barani, A Kasaeian - Journal of Controlled Release, 2017 - Elsevier
Today, the advanced drug delivery systems have been focused on targeted drug delivery
fields. The novel drug delivery is involved with the improvement of the capacity of drug …

Design of nanocarriers for nanoscale drug delivery to enhance cancer treatment using hybrid polymer and lipid building blocks

RX Zhang, T Ahmed, LY Li, J Li, AZ Abbasi, XY Wu - Nanoscale, 2017 - pubs.rsc.org
Polymer–lipid hybrid nanoparticles (PLN) are an emerging nanocarrier platform made from
building blocks of polymers and lipids. PLN integrate the advantages of biomimetic lipid …