Relative hypercoagulopathy of the SARS-CoV-2 beta and delta variants when compared to the less severe omicron variants is related to TEG parameters, the extent of …
LM Grobbelaar, A Kruger, C Venter… - … in thrombosis and …, 2022 - thieme-connect.com
Earlier variants of SARS-CoV-2 have been associated with hypercoagulability and an
extensive formation of fibrin amyloid microclots, which are considered to contribute to the …
extensive formation of fibrin amyloid microclots, which are considered to contribute to the …
Are fibrinaloid microclots a cause of autoimmunity in Long Covid and other post-infection diseases?
DB Kell, E Pretorius - Biochemical Journal, 2023 - portlandpress.com
It is now well established that the blood-clotting protein fibrinogen can polymerise into an
anomalous form of fibrin that is amyloid in character; the resultant clots and microclots entrap …
anomalous form of fibrin that is amyloid in character; the resultant clots and microclots entrap …
The occurrence of hyperactivated platelets and fibrinaloid microclots in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
JM Nunes, A Kruger, A Proal, DB Kell, E Pretorius - Pharmaceuticals, 2022 - mdpi.com
We have previously demonstrated that platelet-poor plasma (PPP) obtained from patients
with Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is characterized by a …
with Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is characterized by a …
TEG®, Microclot and Platelet Mapping for Guiding Early Management of Severe COVID-19 Coagulopathy
GJ Laubscher, PJ Lourens, C Venter, DB Kell… - Journal of clinical …, 2021 - mdpi.com
An important component of severe COVID-19 disease is virus-induced endothelilitis. This
leads to disruption of normal endothelial function, initiating a state of failing normal clotting …
leads to disruption of normal endothelial function, initiating a state of failing normal clotting …
Increasing access to allogeneic hematopoietic cell transplant: an international perspective
V Rocha, G Fatobene, D Niederwieser… - …, 2021 - ashpublications.org
Allogeneic hematopoietic cell transplantation (allo-HCT) is a highly complex, costly
procedure for patients with oncologic, hematologic, genetic, and immunologic diseases …
procedure for patients with oncologic, hematologic, genetic, and immunologic diseases …
Low levels of salivary lactoferrin may affect oral dysbiosis and contribute to Alzheimer's disease: A hypothesis
I Olsen, SK Singhrao - Medical hypotheses, 2021 - Elsevier
Recently it has been reported that reduced levels of salivary lactoferrin (LF) can be a
plausible biomarker for amyloid beta (Aβ) accumulation in Alzheimer's disease (AD) brains …
plausible biomarker for amyloid beta (Aβ) accumulation in Alzheimer's disease (AD) brains …
Functional profile of oral plaque microbiome: Further insight into the bidirectional relationship between type 2 diabetes and periodontitis
Increasing evidence support the association between the oral microbiome and human
systemic diseases. This association may be attributed to the ability of many oral microbes to …
systemic diseases. This association may be attributed to the ability of many oral microbes to …
From the matrix to the nucleus and back: Mechanobiology in the light of health, pathologies, and regeneration of oral periodontal tissues
MP Dieterle, A Husari, T Steinberg, X Wang… - Biomolecules, 2021 - mdpi.com
Among oral tissues, the periodontium is permanently subjected to mechanical forces
resulting from chewing, mastication, or orthodontic appliances. Molecularly, these …
resulting from chewing, mastication, or orthodontic appliances. Molecularly, these …
A comprehensive review on human disease—causing bacterial proteases and their impeding agents
S Sundar, S Piramanayagam, J Natarajan - Archives of Microbiology, 2023 - Springer
Proteases are enzymes that catalyze the amide bond dissociation in polypeptide and protein
peptide units. They are categorized into seven families and are responsible for a wide …
peptide units. They are categorized into seven families and are responsible for a wide …
[HTML][HTML] Cardiovascular and haematological pathology in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): A role for viruses
JM Nunes, DB Kell, E Pretorius - Blood reviews, 2023 - Elsevier
ME/CFS is a debilitating chronic condition that often develops after viral or bacterial
infection. Insight from the study of Long COVID/Post Acute Sequelae of COVID-19 (PASC) …
infection. Insight from the study of Long COVID/Post Acute Sequelae of COVID-19 (PASC) …