Availability of artificial light and light-emitting devices have altered human temporal life,
allowing 24-hour healthcare, commerce and production, and expanding social life around …

Combined chemotherapy is a treatment method based on the simultaneous use of two or
more therapeutic agents; it is frequently necessary to produce a more effective treatment for …

Among cardiovascular diseases, hypertension is one of the main risk factors predisposing to
fatal complications. Oxidative stress and chronic inflammation have been identified as …

Melatonin is a fascinating molecule that has captured the imagination of many scientists
since its discovery in 1958. In recent times, the focus has changed from investigating its …

Melatonin is a neurohormone that is mainly secreted by the pineal gland. It coordinates the
work of the superior biological clock and consequently affects many processes in the human …

Using mass spectrometry‐based targeted metabolomics, we aimed to determine the pattern
of cardiac metabolic reprogramming and energetics in doxorubicin‐induced heart failure …

Ferroptosis, a regulated form of cell death, is characterized by iron-dependent lipid
peroxidation leading to oxidative damage to cell membranes. Cell sensitivity to ferroptosis is …

Septic cardiomyopathy (SCM) is a common complication of sepsis contributing to high
mortality rates. Its pathophysiology involves complex factors, including inflammatory …

Cardiovascular diseases (CVDs) continue to be the leading cause of death in people with
diabetes mellitus. Severely suppressed intracellular antioxidant defenses, including low …

Pineal melatonin and the cortisol awakening response (CAR) are integral aspects of the
circadian rhythm. Pineal melatonin release during sleep is proposed to optimize …