Oxidative stress plays a crucial role in aging-related eye diseases, including age-related
macular degeneration (AMD), cataracts, and glaucoma. With age, antioxidant reparative …

Autoimmune eye diseases (AEDs), a collection of autoimmune inflammatory ocular
conditions resulting from the dysregulation of immune system at the ocular level, can target …

Glaucoma is the leading cause of irreversible blindness. Currently, most therapeutic
strategies aim to reduce elevated intraocular pressure (EIOP), but this does not always halt …

Nerve cell death accounts for various neurodegenerative disorders, in which altered
immunity to the integrated central nervous system (CNS) might have destructive …

Exosomes are membrane-bound tiny particles that are released by all live cells that contain
multiple signal molecules and extensively participate in numerous normal physical activities …

Low intracranial pressure (LICP)–induced translaminar cribrosa pressure difference
(TLCPD) elevation has been proven as a risk factor in glaucomatous neurodegeneration …

Abstract Purpose Retinal ganglion cells (RGCs) are one the most specialized neural tissues
in the body. They transmit (and further process) chemoelectrical information originating in …

Purpose In this study, we aimed to investigate whether Programmed cell death 1 ligand
1/programmed cell death 1 ligand 2 (PD-L1/PD-L2) double knockout (dKO) has a protective …

Glaucoma is a complex neurodegenerative disorder characterized by the progressive loss of
retinal ganglion cells (RGC) and optic nerve axons, leading to irreversible visual impairment …

Background Retinal degeneration is a disease affecting the eye, which is an immune-
privileged site because of its anatomical and physiological properties. Alterations in retinal …