The sirtuin system consists of seven highly conserved regulatory enzymes responsible for
metabolism, antioxidant protection, and cell cycle regulation. The great interest in sirtuins is …

Background: Insulin-like growth factor1 (IGF1) is a polypeptide that structurally is similar to
human pro-insulin, one of the factors that is altered in obesity and many related diseases …

Polycystic ovary syndrome (PCOS) is the most common female endocrine disorder and is
characterized by chronic anovulation, hyperandrogenism, and polycystic ovaries. Obesity …

There is a mechanistic link between the gut-derived metabolite trimethylamine-N-oxide
(TMAO) and obesity-related diseases, suggesting that the TMAO pathway may also be …

Background COVID 19-related quarantine led to a sudden and radical lifestyle changes, in
particular in eating habits. Objectives of the study were to investigate the effect of quarantine …

Growing evidence reported that vitamin D deficiency is a common finding in obesity. Vitamin
D status also seems to be sex-related, although little is known regarding this association …

Phase angle (PhA), a noninvasive bioimpedance marker, is a useful tool for nutritional
screening in several diseases. C-reactive protein (CRP), a strong risk factor for metabolic …

Background Obesity, mainly visceral obesity, and metabolic syndrome (MetS) are major risk
factors for the development of type 2 diabetes, cardiovascular diseases, and cancer. Data …

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
in the industrialized world. The prevalence of NAFLD is increasing, becoming a substantial …

Vitamin D deficiency and obesity are two public health problems extensively exacerbated
over the last years. Among the several mechanisms proposed to account for the complex …