[HTML][HTML] Immunosuppression for immune-related adverse events during checkpoint inhibition: an intricate balance
RJ Verheijden, MJM van Eijs, AM May… - NPJ precision …, 2023 - nature.com
Immune checkpoint inhibitors (ICIs) have changed perspectives for patients with cancer, but
come with severe immune-related adverse events (irAEs). To prevent fatality or chronicity …
come with severe immune-related adverse events (irAEs). To prevent fatality or chronicity …
Stocking the toolbox—Using preclinical models to understand the development and treatment of immune checkpoint inhibitor‐induced immune‐related adverse …
ML Cina, J Venegas, A Young - Immunological Reviews, 2023 - Wiley Online Library
Cancer patients treated with immune checkpoint inhibitors (ICIs) are susceptible to a broad
and variable array of immune‐related adverse events (irAEs). With increasing clinical use of …
and variable array of immune‐related adverse events (irAEs). With increasing clinical use of …
[HTML][HTML] Neutrophil extracellular traps (NETs)-related lncRNAs signature for predicting prognosis and the immune microenvironment in breast cancer
T Jiang, Y Wang, X Chen, W Xia, S Xue… - Frontiers in Cell and …, 2023 - frontiersin.org
Background: Neutrophil extracellular traps (NETs) are closely associated to tumorigenesis
and development. However, the relationship between NETs-related long non-coding RNAs …
and development. However, the relationship between NETs-related long non-coding RNAs …
[HTML][HTML] Loss of MHC-I antigen presentation correlated with immune checkpoint blockade tolerance in MAPK inhibitor-resistant melanoma
J Yu, X Wu, J Song, Y Zhao, H Li, M Luo… - Frontiers in …, 2022 - frontiersin.org
Immune checkpoint blockade and MAPK-targeted combined therapy is a promising regimen
for advanced melanoma patients. However, the clinical benefit from this combo regimen …
for advanced melanoma patients. However, the clinical benefit from this combo regimen …
[HTML][HTML] Crosstalk between metabolism and immune activity reveals four subtypes with therapeutic implications in clear cell renal cell carcinoma
Y Wang, XD Zheng, GQ Zhu, N Li, CW Zhou… - Frontiers in …, 2022 - frontiersin.org
Clear cell renal cell carcinoma (ccRCC) is characterized by metabolic dysregulation and
distinct immunological signatures. The interplay between metabolic and immune processes …
distinct immunological signatures. The interplay between metabolic and immune processes …
[HTML][HTML] Immunotherapy for hepatocellular carcinoma recurrence after liver transplantation, can we harness the power of immune checkpoint inhibitors?
J Jiang, H Huang, R Chen, Y Lin, Q Ling - Frontiers in Immunology, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death
globally and liver transplantation (LT) can serve as the best curative treatment option …
globally and liver transplantation (LT) can serve as the best curative treatment option …
Integrated network pharmacology and gut microbiome analysis to reveal the mechanism of Qu-Zhuo-Tong-Bi decoction against hyperuricemia and gout
S Song, M Fan, X Wen, X Shi, Y Lou, Z He… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Qu-zhuo-tong-bi decoction (QZTBD) is a classic Chinese
herbal medicine that has shown therapeutic efficacy in clinical practice against …
herbal medicine that has shown therapeutic efficacy in clinical practice against …
[HTML][HTML] Genetic dysregulation of immunologic and oncogenic signaling pathways associated with tumor-intrinsic immune resistance: a molecular basis for …
KM Hargadon - Cellular and Molecular Life Sciences, 2023 - Springer
Since the turn of the century, advances in targeted therapy and immunotherapy have
revolutionized the treatment of cancer. Although these approaches have far outperformed …
revolutionized the treatment of cancer. Although these approaches have far outperformed …
[HTML][HTML] IFN-γ decreases PD-1 in T lymphocytes from convalescent COVID-19 patients via the AKT/GSK3β signaling pathway
M Song, X Liu, W Shen, Z Wang, J Wu, J Jiang, Y Liu… - Scientific Reports, 2024 - nature.com
Post-COVID-19 syndrome may be associated with the abnormal immune status. Compared
with the unexposed age-matched elder group, PD-1 in the CD8+ T cells from recovered …
with the unexposed age-matched elder group, PD-1 in the CD8+ T cells from recovered …
[HTML][HTML] Artificial intelligence-assisted transcriptomic analysis to advance cancer immunotherapy
Y Gui, X He, J Yu, J Jing - Journal of Clinical Medicine, 2023 - mdpi.com
The emergence of immunotherapy has dramatically changed the cancer treatment paradigm
and generated tremendous promise in precision medicine. However, cancer immunotherapy …
and generated tremendous promise in precision medicine. However, cancer immunotherapy …