The nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3)
inflammasome is an important part of the natural immune system that plays an important role …

Depression is a common psychiatric disorder under the category of depression syndrome in
Traditional Chinese Medicine (TCM) theory. Meanwhile, Xiaochaihu Decoction is a classical …

Objectives Diabetic nephropathy (DN) is the most common microvascular complication of
diabetes mellitus. This study investigated the mechanism of triptolide (TP) in podocyte injury …

Estrogen receptors (ERs) are transcription factors with two subtypes: estrogen receptor
alpha (ERα) and estrogen receptor beta (ERβ), which are essential for the maintenance of …

Background Liver fibrosis (LF) is a trauma repair process carried out by the liver in response
to various acute and chronic liver injuries. Its primary pathological characteristics are …

Cellular senescence plays a very important role in the ageing of organisms and age-related
diseases that increase with age, a process that involves physiological, structural …

Truncated transforming growth factor β receptor type II (tTβRII) is a promising anti-liver
fibrotic candidate because it serves as a trap for binding excessive TGF-β1 by means of …

Objective. To explore the function and mechanism of Sirt‐1 in fluorine‐induced liver injury.
Method. Fluorosis rats were first established. The fluorine content, pathological structure …

Ethnopharmacological relevance Bupleuri Radix (BR) has been recognized as an essential
herbal medicine for relieving liver depression for thousands of years. Contemporary …

Ulcerative colitis (UC) is a part of the cluster of conditions–known as inflammatory bowel
disease. It is caused by a plethora of factors that on a long-term basis result in inflammation …