Exosomes: the next generation of endogenous nanomaterials for advanced drug delivery and therapy
W Liao, Y Du, C Zhang, F Pan, Y Yao, T Zhang, Q Peng - Acta biomaterialia, 2019 - Elsevier
Abstract Development of functional nanomaterials is of great importance and significance for
advanced drug delivery and therapy. Nevertheless, exogenous nanomaterials have a great …
advanced drug delivery and therapy. Nevertheless, exogenous nanomaterials have a great …
Theranostic nanoparticles with disease-specific administration strategies
Recent advances in the synthesis of nanomaterials with diagnostic and therapeutic
capabilities have been rapidly reshaping the landscape of precision medicine. Impressive …
capabilities have been rapidly reshaping the landscape of precision medicine. Impressive …
Nanoparticles for oral delivery: targeted therapy for inflammatory bowel disease
D Li, M Yang, H Xu, M Zhu, Y Zhang, C Tian… - Journal of Materials …, 2022 - pubs.rsc.org
As a group of chronic and idiopathic gastrointestinal (GI) disorders, inflammatory bowel
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …
Protein corona formed in the gastrointestinal tract and its impacts on oral delivery of nanoparticles
T Zhang, G Zhu, B Lu, Z Qian… - Medicinal research …, 2021 - Wiley Online Library
The interaction of nanoparticles (NPs) with proteins and the formation of protein corona in
the biological fluids are of great interest and significance for drug delivery. In the past …
the biological fluids are of great interest and significance for drug delivery. In the past …
Lipid-based drug delivery nanoplatforms for colorectal cancer therapy
Colorectal cancer (CRC) is a prevalent disease worldwide, and patients at late stages of
CRC often suffer from a high mortality rate after surgery. Adjuvant chemotherapeutics (ACs) …
CRC often suffer from a high mortality rate after surgery. Adjuvant chemotherapeutics (ACs) …
Uptake of functional ultrasmall gold nanoparticles in 3D gut cell models
V Sokolova, JF Ebel, S Kollenda, K Klein, B Kruse… - Small, 2022 - Wiley Online Library
Ultrasmall gold nanoparticles (2 nm) easily penetrate the membranes of intestinal murine
epithelial cells (MODE‐K) and colorectal cancer cells (CT‐26). They are also taken up by 3D …
epithelial cells (MODE‐K) and colorectal cancer cells (CT‐26). They are also taken up by 3D …
Digestive enzyme corona formed in the gastrointestinal tract and its impact on epithelial cell uptake of nanoparticles
Q Peng, J Liu, T Zhang, TX Zhang, CL Zhang… - …, 2019 - ACS Publications
The fate of intravenously injected nanoparticles (NPs) is significantly affected by nano-
protein interaction and corona formation. However, such an interaction between NPs and …
protein interaction and corona formation. However, such an interaction between NPs and …
Encapsulation of phycocyanin by prebiotics and polysaccharides-based electrospun fibers and improved colon cancer prevention effects
Y Wen, P Wen, TG Hu, RJ Linhardt, MH Zong… - International journal of …, 2020 - Elsevier
To preserve bioactivity and achieve colon targeted release of phycocyanin (PC), the
polysaccharides-based electrospun fiber mat (EFM) containing PC and prebiotics was …
polysaccharides-based electrospun fiber mat (EFM) containing PC and prebiotics was …
Smart polymers for colon targeted drug delivery systems: a review
MK Sarangi, MEB Rao, V Parcha - International Journal of …, 2021 - Taylor & Francis
The colon targeted drug delivery has a number of important implications in the field of
pharmacotherapy. Oral colon targeted drug delivery systems have recently gained …
pharmacotherapy. Oral colon targeted drug delivery systems have recently gained …
In vitro and in vivo models for evaluating the oral toxicity of nanomedicines
S Lama, O Merlin-Zhang, C Yang - Nanomaterials, 2020 - mdpi.com
Toxicity studies for conventional oral drug formulations are standardized and well
documented, as required by the guidelines of administrative agencies such as the US Food …
documented, as required by the guidelines of administrative agencies such as the US Food …