Chronic social stressors and striatal dopamine functioning in humans: A systematic review of SPECT and PET studies

R Schalbroeck, CFM van Hooijdonk, DPA Bos… - Molecular …, 2024 - nature.com
The dopamine hypothesis of schizophrenia posits that elevated striatal dopamine
functioning underlies the development of psychotic symptoms. Chronic exposure to social …

Recent applications of positron emission tomographic (PET) imaging in psychiatric drug discovery

L Zimmer - Expert Opinion on Drug Discovery, 2024 - Taylor & Francis
Introduction Psychiatry is one of the medical disciplines that suffers most from a lack of
innovation in its therapeutic arsenal. Many failures in drug candidate trials can be explained …

Preclinical and clinical imaging techniques as pathophysiological biomarkers—A preface to the special issue “Brain Imaging”

VL Villemagne, Y Li - Journal of Neurochemistry, 2023 - Wiley Online Library
Molecular imaging techniques have become important tools to characterize and measure
biological processes at the cellular and molecular levels. Nowadays, molecular imaging …