[HTML][HTML] Liposomes in cancer therapy: how did we start and where are we now

MD Fulton, W Najahi-Missaoui - International Journal of Molecular …, 2023 - mdpi.com
Since their first discovery in the 1960s by Alec Bangham, liposomes have been shown to be
effective drug delivery systems for treating various cancers. Several liposome-based …

[HTML][HTML] Liposomal drug delivery systems and anticancer drugs

TOB Olusanya, RR Haj Ahmad, DM Ibegbu, JR Smith… - Molecules, 2018 - mdpi.com
Cancer is a life-threatening disease contributing to~ 3.4 million deaths worldwide. There are
various causes of cancer, such as smoking, being overweight or obese, intake of processed …

[HTML][HTML] Advances and challenges of liposome assisted drug delivery

L Sercombe, T Veerati, F Moheimani, SY Wu… - Frontiers in …, 2015 - frontiersin.org
The application of liposomes to assist drug delivery has already had a major impact on
many biomedical areas. They have been shown to be beneficial for stabilizing therapeutic …

Nanoparticles as carriers for drug delivery in cancer

A Dadwal, A Baldi, R Kumar Narang - Artificial cells, nanomedicine …, 2018 - Taylor & Francis
Cancer nanotherapeutics are swiftly progressing and are being applied to solve several
limitations of conventional drug delivery systems such as non-specific biodistribution and …

Nanocarriers as an emerging platform for cancer therapy

D Peer, JM Karp, S Hong, OC Farokhzad… - Nano-enabled …, 2020 - taylorfrancis.com
The delivery of drugs through targeted nanocarriers that are internalized by cells provides
an alternative route to diffusion of drugs into cells. Growth factor or vitamin interactions with …

[HTML][HTML] Lipid nanoparticle mRNA systems containing high levels of sphingomyelin engender higher protein expression in hepatic and extra-hepatic tissues

N Chander, G Basha, MHY Cheng… - … Therapy-Methods & …, 2023 - cell.com
Lipid nanoparticles (LNPs) for delivery of mRNA usually contain ionizable lipid/helper
lipid/cholesterol/PEG-lipid in molar ratios of 50: 10: 38.5: 1.5, respectively. These LNPs are …

Solid lipid nanoparticles: production, characterization and applications

W Mehnert, K Mäder - Advanced drug delivery reviews, 2012 - Elsevier
Solid lipid nanoparticles (SLN) have attracted increasing attention during recent years. This
paper presents an overview about the selection of the ingredients, different ways of SLN …

Long-circulating and target-specific nanoparticles: theory to practice

SM Moghimi, AC Hunter, JC Murray - Pharmacological reviews, 2001 - ASPET
The rapid recognition of intravenously injected colloidal carriers, such as liposomes and
polymeric nanospheres from the blood by Kupffer cells, has initiated a surge of development …

Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties

SM Moghimi, J Szebeni - Progress in lipid research, 2003 - Elsevier
This article critically examines and evaluates the likely mechanisms that contribute to
prolonged circulation times of sterically protected nanoparticles and liposomes. It is …

Novel applications of liposomes

DD Lasic - Trends in biotechnology, 1998 - cell.com
Opinions of the usefulness of liposomes in various biotechnological applications range from
unsubstantiated optimism to undeserved pessimism. This article reviews the background …