Menopause is clinically diagnosed as a condition when a woman has not menstruated for
one year. During the menopausal transition period, there is an emergence of various lipid …

The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

Sex hormones strongly influence body fat distribution and adipocyte differentiation.
Estrogens and testosterone differentially affect adipocyte physiology, but the importance of …

Energy metabolism in humans is tuned to distinct sex-specific functions that potentially
reflect the unique requirements in females for gestation and lactation, whereas male …

Many questions must be considered with regard to consuming food, including when to eat,
what to eat and how much to eat. Although eating is often thought to be a homeostatic …

Dichlorodiphenyltrichloroethane (DDT) has been used extensively to control malaria,
typhus, body lice and bubonic plague worldwide, until countries began restricting its use in …

Decreased estrogens during menopause are associated with increased risk of anxiety,
depression, type 2 diabetes and obesity. Similarly, depleting estrogens in rodents by …

Lipoprotein synthesis is controlled by estrogens, but the exact mechanisms underpinning
this regulation and the role of the hepatic estrogen receptor α (ERα) in cholesterol …

It is clear that insulin-like growth factor-1 (IGF1) is important in supporting growth and
regulating metabolism. The IGF1 found in the circulation is primarily produced by the liver …

Oxidative stress (OS), as a signal of aberrant intracellular mechanisms, plays key roles in
maintaining homeostasis for organisms. The occurrence of OS due to the disorder of normal …