Patients with chronic kidney disease (CKD) are at an increased risk of premature mortality,
mainly from cardiovascular causes. The association between CKD on hemodialysis and …

Approximately 20% to 40% of patients with type 1 or type 2 diabetes mellitus develop
diabetic kidney disease. This is a clinical syndrome characterized by persistent albuminuria …

Results Of 37 individuals randomized (age= 69±10 years old; 57% men; eGFR= 24±8
ml/min per 1.73 m 2), 31 completed the study. Synbiotic therapy did not significantly reduce …

Results Plasma levels of IL-1β, IL-1RA, IL-6, TNF-α, hs-CRP, and fibrinogen were higher
among participants with lower levels of eGFR. Inflammation score was higher among those …

Homeostasis is a prerequisite for health. When homeostasis becomes disrupted, dysfunction
occurs. This is especially the case for the gut microbiota, which under normal conditions …

Cardiovascular diseases such as coronary artery disease, congestive heart failure,
arrhythmias and sudden cardiac death represent main causes of morbidity and mortality in …

Before the introduction of erythropoiesis-stimulating agents (ESAs) in 1989, repeated
transfusions given to patients with end-stage renal disease caused iron overload, and the …

Background: Patients with end-stage renal disease (ESRD) have elevated serum levels of
inflammatory mediators including C-reactive protein (CRP), tumor necrosis factor-α (TNF-α) …

Although previous studies in the general population showed that hypomagnesemia is a risk
for cardiovascular diseases (CVD), the impact of magnesium on the prognosis of patients on …

Proinflammatory cytokines contribute to renal injury, but the downstream effectors within
kidney cells are not well understood. One candidate effector is Klotho, a protein expressed …