Diabetes mellitus is associated with a high risk of developing gastric cancer (GC). Metformin,
which is conventionally used to treat type 2 diabetes, induces AMP-activated protein kinase …

Combination therapy has long been applied to enhance therapeutic effect and deal with the
occurrence of multi-drug resistance in cancer treatment. However, the overlapping toxicity of …

Osteoarthritis (OA) and type 2 diabetes mellitus (T2D) are two of the most widespread
chronic diseases. OA and T2D have common epidemiologic traits, are considered …

Gestational diabetes mellitus (GDM) is a disease of pregnancy that is associated with d-
glucose intolerance and foeto-placental vascular dysfunction. GMD causes mitochondrial …

In the face of global pathogens such as influenza (flu) and severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), strategies beyond standard vaccines and virus …

Metformin (MET) and atorvastatin (ATO) are promising treatments for COVID-19. This review
explores the potential of MET and ATO, commonly prescribed for diabetes and dyslipidemia …

Metformin is considered the first-choice drug for type 2 diabetes treatment. Actually,
pleiotropic effects of metformin have been recognized, and there is evidence that this drug …

Metformin is a widely used drug for type 2 diabetes that is considered to have potential anti-
aging effects. However, the beneficial effects of metformin in middle-aged normoglycemic …

Over the past decade, knowledge of cancer metabolism has expanded exponentially and
has provided several clinically relevant targets for cancer therapy. Although these current …

This study investigated the influence of dietary phenolic acid-Gallic acid (GA) on the
antihyperglycemic properties of acarbose (ACA) and metformin (MET). Streptozotocin …