Metabolically healthy obesity: facts and fantasies

GI Smith, B Mittendorfer, S Klein - The Journal of clinical …, 2019 - Am Soc Clin Investig
Although obesity is typically associated with metabolic dysfunction and cardiometabolic
diseases, some people with obesity are protected from many of the adverse metabolic …

[HTML][HTML] Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus

MS Burhans, DK Hagman, JN Kuzma… - Comprehensive …, 2018 - ncbi.nlm.nih.gov
The objective of this comprehensive review is to summarize and discuss the available
evidence of how adipose tissue inflammation affects insulin sensitivity and glucose …

Metabolically healthy obesity: criteria, epidemiology, controversies, and consequences

A Tsatsoulis, SA Paschou - Current obesity reports, 2020 - Springer
Abstract Purpose of Review To present a comprehensive overview regarding criteria,
epidemiology, and controversies that have arisen in the literature about the existence and …

Metabolically healthy obesity and cardiovascular events: a systematic review and meta-analysis

N Eckel, K Meidtner, T Kalle-Uhlmann… - European journal of …, 2016 - journals.sagepub.com
Aims Previous studies have provided inconsistent results about the cardiovascular risks for
participants with metabolically healthy obesity (MHO). These uncertainties might partly …

The relationship between obesity and hypertension: an updated comprehensive overview on vicious twins

M Leggio, M Lombardi, E Caldarone, P Severi… - Hypertension …, 2017 - nature.com
Obesity is a growing global health concern, with a rapid increase being observed in morbid
obesity. Obesity is associated with an increased cardiovascular risk and earlier onset of …

Chronic inflammation in obesity and the metabolic syndrome

R Monteiro, I Azevedo - Mediators of inflammation, 2010 - Wiley Online Library
The increasing incidence of obesity and the metabolic syndrome is disturbing. The activation
of inflammatory pathways, used normally as host defence, reminds the seriousness of this …

The prevalence of metabolically healthy obesity: a systematic review and critical evaluation of the definitions used

JP Rey‐López, LF De Rezende… - Obesity …, 2014 - Wiley Online Library
We performed a systematic review of the prevalence of metabolically healthy obesity (MHO).
Medline, W eb of S cience and EMBASE were searched for original articles from inception to …

Characterizing the profile of obese patients who are metabolically healthy

V Primeau, L Coderre, AD Karelis, M Brochu… - International journal of …, 2011 - nature.com
The presence of obesity-related metabolic disturbances varies widely among obese
individuals. Accordingly, a unique subset of obese individuals has been described in the …

Metabolically healthy obesity: definitions, determinants and clinical implications

CM Phillips - Reviews in Endocrine and Metabolic Disorders, 2013 - Springer
Obesity is associated with increased risk of developing metabolic syndrome (MetS), type 2
diabetes mellitus (T2DM) and cardiovascular disease (CVD) leading to higher all-cause …

Metabolically healthy obesity and the risk of cardiovascular disease and type 2 diabetes: the Whitehall II cohort study

GM Hinnouho, S Czernichow, A Dugravot… - European heart …, 2015 - academic.oup.com
Aim The metabolically healthy obese (MHO) phenotype refers to obese individuals with a
favourable metabolic profile. Its prognostic value is unclear and may depend on the health …