Polymer-based drug delivery depots have been investigated over the last several decades
as a means to improve upon the lack of tumor targeting and severe systemic morbidities …

Metastasis resistant to therapy is the major cause of death from cancer. Despite almost 200
years of study, the process of tumor metastasis remains controversial. Stephen Paget initially …

A number of successful systemic therapies are available for treatment of disseminated
cancers. However, tumor response is often transient, and therapy frequently fails due to …

Background Even small delays in the treatment of breast cancer are a frequently expressed
concern of patients. Knowledge about this subject is important for clinicians to counsel …

Interest in tumour pH stems from the early part of this century, when the pioneering work of
Otto Warburg first suggested that aerobic glycolysis was a characteristic property of …

Conclusions In a large Western cohort of patients with HCC, we found heterogeneous tumor
growth patterns, with one‐fourth exhibiting rapid growth and over one‐third having indolent …

Patients with Beckwith–Wiedemann syndrome (BWS) have an increased risk to develop
cancer in childhood, especially Wilms tumor and hepatoblastoma. The risk varies depending …

PURPOSE: To synthesize the direct clinical evidence relating waiting times (WTs) for
radiotherapy (RT) to the outcomes of RT. METHODS AND MATERIALS: We did a systematic …

Testicular carcinomas, pediatric tumors, and some mesenchymal tumors are examples of
rapidly proliferating cell populations, for which the tumor volume doubling time (TVDT) can …

We analyzed the growth pattern of tumor masses and the survival of 39 asymptomatic Italian
patients with a total of 59 small (⩽ 5 cm in diameter) hepatocellular carcinomas arising from …