Inflammatory bowel disease (IBD) is associated with the production of reactive species that
target cysteine redox switches in proteins, thereby affecting gene regulation, DNA damage …

Inflammatory bowel disease (IBD) comprises ulcerative colitis (UC) and Crohn's disease
(CD). IBD etiopathology is multifactorial and involves alteration of immune cells and chronic …

A human gut-on-a-chip microdevice was used to coculture multiple commensal microbes in
contact with living human intestinal epithelial cells for more than a week in vitro and to …

The organic cation transporters (OCTs) OCT1, OCT2, OCT3, novel OCT (OCTN) 1, OCTN2,
multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …

Gut microbiota has a fundamental role in the energy homeostasis of the host and is essential
for proper “education” of the immune system. Intestinal microbial communities are able to …

MicroRNA (miRNA)-mediated RNA interference regulates many immune processes, but how
miRNA circuits orchestrate aberrant intestinal inflammation during inflammatory bowel …

Objective The inner mucus layer in mouse colon normally separates bacteria from the
epithelium. Do humans have a similar inner mucus layer and are defects in this mucus layer …

We evaluated immunometabolic functions of novel Lactobacillus fermentum strains (KBL374
and KBL375) isolated from feces of healthy Koreans. The levels of inflammatory cytokines …

The ultimate goal of most biomedical research is to gain greater insight into mechanisms of
human disease or to develop new and improved therapies or diagnostics. Although great …

Crohn's disease (CD) and ulcerative colitis (UC), two forms of inflammatory bowel disease
(IBD), are chronic, relapsing, and tissue destructive lesions that are accompanied by the …