Primary ovarian insufficiency (POI) is a rare gynecological condition. This disease causes
menstrual disturbances, infertility, and various health problems. Historically, hormone …

Premature ovarian insufficiency (POI) is a condition that arises from dysfunction or early
depletion of the ovarian follicle pool accompanied by an earlier-than-normal loss of fertility in …

Premature ovarian insufficiency (POI) is clinically irreversible in women aged over 40 years.
Although numerous studies have demonstrated satisfactory outcomes of mesenchymal stem …

The negative effect of oxidative stress on the human reproductive process is no longer a
matter for debate. Oxidative stress affects female and male gametes and the developmental …

Background: Granulosa cell (GC) apoptosis is the main cause of follicular atresia, and
oxidative stress is involved in this process. Results: GC apoptosis is caused by FoxO1 …

Thus far, the potential short-and long-term detrimental effects of a variety of environmental
chemicals designated as endocrine-active compounds (EACs) have been found to interfere …

Reproductive aging is on the rise globally and inseparable from the entire aging process. An
extreme form of reproductive aging is premature ovarian insufficiency (POI), which to date …

Primary ovarian insufficiency (POI) is defined by the loss or dysfunction of ovarian follicles
associated with amenorrhea before the age of 40. Symptoms include hot flashes, sleep …

Increasingly, mitochondria are being recognized as having an important role in fertility.
Indeed in assisted reproductive technologies mitochondrial function is a key indicator of …

Premature ovarian insufficiency (POI) is a common cause of infertility in women,
characterised by amenorrhea and elevated FSH under the age of 40 years. In some cases …