CD8 T cells play crucial roles in immune surveillance and defense against infections and
cancer. After encountering antigenic stimulation, naïve CD8 T cells differentiate and acquire …

The majority of colorectal cancer patients are not responsive to immune checkpoint
blockade (ICB). The interferon gamma (IFNγ) signaling pathway drives spontaneous and …

Fatty acid composition in the Western diet has shifted from saturated to polyunsaturated fatty
acids (PUFAs), and specifically to linoleic acid (LA, 18: 2), which has gradually increased in …

CD8+ lymphocytes are adaptive immunity cells with the particular function to directly kill the
target cell following antigen recognition in the context of MHC class I. In addition, CD8+ T …

Stroke is a severe and life-threatening disease, necessitating more research on new
treatment strategies. Infiltrated T lymphocytes, an essential adaptive immune cell with …

The generation of memory is a cardinal feature of the adaptive immune response, involving
different factors in a complex process of cellular differentiation. This process is essential for …

CD8+ T cells are a crucial part of the adaptive immune system, responsible for combating
intracellular pathogens and tumor cells. The initial activation of T cells involves the formation …

Neutrophils are the first migrating responders to sterile and infectious inflammation and act
in a powerful but nonspecific fashion to kill a wide variety of pathogens. It is now apparent …

Human African trypanosomiasis (HAT) is a neglected tropical disease that is caused by
flagellated parasites of the genus Trypanosoma. HAT imposes a significant socio-economic …

Cytokine release syndrome (CRS) is a lethal adverse event in chimeric antigen receptor
(CAR) T‐cell therapy, hindering this promising therapy for cancers, such as B‐cell acute …