Standardization and quality control studies of 'real-time'quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease …

J Gabert, E Beillard, VHJ Van der Velden, W Bi… - Leukemia, 2003 - nature.com
Detection of minimal residual disease (MRD) has proven to provide independent prognostic
information for treatment stratification in several types of leukemias such as childhood acute …

Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia

BJ Druker, NB Lydon - The Journal of clinical investigation, 2000 - Am Soc Clin Investig
AProtein kinase targeted. A number of these molecules are broad-spectrum kinase
inhibitors. BStaurosporine class represents examples of broad-spectrum kinase inhibitors …

Minimal residual disease in leukaemia patients

T Szczepariski, A Orfão, VHJ van der Valden… - The lancet …, 2001 - thelancet.com
Because of developments in diagnosis of haemopoietic malignant diseases during the past
two decades, routine and reliable identification of very low numbers of malignant cells …

Comparison of chromosome banding analysis, interphase-and hypermetaphase-FISH, qualitative and quantitative PCR for diagnosis and for follow-up in chronic …

C Schoch, S Schnittger, S Bursch, D Gerstner… - Leukemia, 2002 - nature.com
For the diagnosis of CML and for monitoring of treatment response the detection of the t (9;
22)(q34; q11) or the BCR-ABL rearrangement is necessary. Chromosome banding analysis …

Durability of responses following donor lymphocyte infusions for patients who relapse after allogeneic stem cell transplantation for chronic myeloid leukemia

F Dazzi, RM Szydlo, NCP Cross… - Blood, The Journal …, 2000 - ashpublications.org
An analysis was performed of the response to treatment with donor lymphocyte infusions
(DLI) and the survival in 66 consecutive patients who relapsed after primary treatment by …

Early detection of BCR-ABL transcripts by quantitative reverse transcriptase–polymerase chain reaction predicts outcome after allogeneic stem cell transplantation for …

E Olavarria, E Kanfer, R Szydlo, J Kaeda… - Blood, The Journal …, 2001 - ashpublications.org
The reverse transcriptase–polymerase chain reaction (RT-PCR) has become widely used
for monitoring minimal residual disease after allogeneic stem cell transplantation (SCT) for …

[HTML][HTML] Increasing Immune Dysfunction is Associated with Increasing Matrix-Metalloproteinase-2 Expression and Predicts Biochemical Failure in Men with Bone …

NP Murray, S Aedo, C Fuentealba… - Asian Pacific Journal …, 2022 - ncbi.nlm.nih.gov
Results: 402 men underwent radical prostatectomy, one month post surgery 79 men were
positive for only bone marrow micro-metastasis and formed the study group; of whom 36/79 …

Detection of minimal residual disease

G Dölken - 2001 - Elsevier
A high percentage of patients with leukemia, lymphoma, and solid tumors achieve a
complete clinical remission after initial treatment, but the majority of these patients will finally …

[HTML][HTML] The possible role of matrix metalloprotienase-2 in the relapse in patients with stage II colon cancer treated by curative surgery

NP Murray, R Villalon, S Aedo… - Asian Pacific Journal …, 2023 - ncbi.nlm.nih.gov
Aims: To determine the association of micro-metastatic matrix metalloproteinase-2 (MMP-2)
expression, the absolute lymphocyte count (ALC)) and outcome in stage II colon cancer …

Investigating the platelet-sparing mechanism of paclitaxel/carboplatin combination chemotherapy

E Pertusini, J Ratajczak, M Majka… - Blood, The Journal …, 2001 - ashpublications.org
Paclitaxel and carboplatin chemotherapy is reported to be a platelet-sparing drug
combination. This study investigated potential mechanisms for this observation by studying …