Several articles have dealt with the importance and mechanisms of the sympathetic nervous
system alterations in experimental animal models of hypertension. This review addresses …

The seminal role of hypertension in the pathogenesis of the cardiorenal metabolic syndrome
(CRS) has significantly evolved over the past 5 years. The physiology of this is rooted in the …

Translational medicine is concerned with the translation of research discoveries into clinical
applications for the prevention, diagnosis, and treatment of human diseases. Here we briefly …

Autonomic cardiovascular control is impaired in hypertension, leading to a reduction in the
parasympathetic tone and to an increase in the sympathetic influences to the heart and …

Worldwide, obesity trends are causing serious public health concern and in many countries
threatening the viability of basic health care delivery. It is an independent risk factor for …

A neurogenic component to primary hypertension (hypertension) is now well established.
Along with raised vasomotor tone and increased cardiac output, the chronic activation of the …

The world wide prevalence of obesity and the metabolic syndrome is escalating. Contrary to
earlier experimental evidence, human obesity is characterised by sympathetic nervous …

Studies performed in the past two decades have unequivocally shown that several of the
components of the metabolic syndrome are associated with indirect and direct markers of …

differences between studies in the form of dietary loading (namely, chow-fed, high fat, or
glucose-enriched), the common response was rapid weight gain, sympathetic nervous …

Excess body weight is a major risk factor for cardiovascular disease, increasing the risk of
hypertension, hyperglycaemia and dyslipidaemia, recognized as the metabolic syndrome …