The first trimester placenta is very rarely investigated for placental vascular formation in
developmental or diseased contexts. Defects in placental formation can cause heart defects …

Genetic factors play a significant role in the pathogenesis of mitral valve diseases, including
mitral valve prolapse (MVP) and mitral valve regurgitation. Genes like Fibrillin-1 (FBN1) …

Pathological neovascularization is a pivotal biological process in wet age-related macular
degeneration (AMD), retinopathy of prematurity (ROP) and proliferative diabetic retinopathy …

Skeletal muscle has a unique ability to remodel in response to stimuli such as contraction
and aerobic exercise training. Phenotypic changes in muscle that occur with training such as …

BACKGROUND: New blood vessel formation requires endothelial cells to transition from a
quiescent to an invasive phenotype. Transcriptional changes are vital for this switch, but a …

Senescent kidney can lead to the maladaptive repairment and predispose age‐related
kidney diseases. Here, we explore the renal anti‐senescence effect of a known kind of drug …

PURPOSE To determine retinal detachment (RD) risk factors after lens removal surgery in
children with Marfan syndrome (MS). DESIGN Retrospective, case control study. METHODS …

Objective: To determine the profile of inflammation-related proteins and complement system
factors in serum of CRB1-associated inherited retinal dystrophies (CRB1-IRDs). Design: A …

Background The long non-coding RNA (lncRNA) Opa interacting protein 5-antisense RNA 1
(OIP5-AS1) has been shown to participate in numerous biological and pathological …

One of the foremost targets in the advancement of biomaterials to engineer vascularized
tissues is not only to replicate the composition of the intended tissue but also to create …