[HTML][HTML] A review on chikungunya virus epidemiology, pathogenesis and current vaccine development

TYV de Lima Cavalcanti, MR Pereira, SO de Paula… - Viruses, 2022 - mdpi.com
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that recently re-emerged in
many parts of the world causing large-scale outbreaks. CHIKV infection presents as a febrile …

[HTML][HTML] TLRs: innate immune sentries against SARS-CoV-2 infection

S Mantovani, B Oliviero, S Varchetta, A Renieri… - International Journal of …, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has been responsible for a devastating pandemic since March …

Distinct cellular tropism and immune responses to alphavirus infection

NM Kafai, MS Diamond, JM Fox - Annual review of immunology, 2022 - annualreviews.org
Alphaviruses are emerging and reemerging viruses that cause disease syndromes ranging
from incapacitating arthritis to potentially fatal encephalitis. While infection by arthritogenic …

[HTML][HTML] Toll-like receptors as pro-thrombotic drivers in viral infections: a narrative review

B Panzer, CW Kopp, C Neumayer, R Koppensteiner… - Cells, 2023 - mdpi.com
Toll-like receptors (TLRs) have a critical role in the pathogenesis and disease course of viral
infections. The induced pro-inflammatory responses result in the disturbance of the …

COVID-19 susceptibility, severity, clinical outcome and Toll-like receptor (7) mRNA expression driven by TLR7 gene polymorphism (rs3853839) in middle-aged …

SM El-Hefnawy, HA Eid, RG Mostafa, SS Soliman… - Gene Reports, 2022 - Elsevier
Background Toll-like receptors are implicated in the pathophysiology of the severe acute
respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory disease …

COVID19 in South Asians/Asian Indians: Heterogeneity of data and implications for pathophysiology and research

R Gupta, A Misra - Diabetes research and clinical practice, 2020 - Elsevier
Despite a large population and limited health infrastructure, the incidence and mortality of
Coronavirus Disease 2019 (COVID-19) has been lower in South Asia than many regions …

Chikungunya virus infection induces differential inflammatory and antiviral responses in human monocytes and monocyte-derived macrophages

VLJ Felipe, UI Silvio - Acta tropica, 2020 - Elsevier
Chikungunya virus (CHIKV) is a zoonotic arthropod-borne virus that has caused several
outbreaks in tropical and subtropical areas worldwide during the last 50 years. The virus is …

[HTML][HTML] Genetic determinants of the re-emergence of arboviral diseases

H Ketkar, D Herman, P Wang - Viruses, 2019 - mdpi.com
Mosquito-borne diseases constitute a large portion of infectious diseases, causing more
than 700,000 deaths annually. Mosquito-transmitted viruses, such as yellow fever, dengue …

[HTML][HTML] Study of kaempferol in the treatment of COVID-19 combined with Chikungunya co-infection by network pharmacology and molecular docking technology

MA Hossain, M Sohel, T Sultana, MI Hasan… - Informatics in Medicine …, 2023 - Elsevier
Chikungunya (CHIK) patients may be vulnerable to coronavirus disease (COVID-19).
However, presently there are no anti-COVID-19/CHIK therapeutic alternatives available. The …

[HTML][HTML] Association of TLR4 and TLR9 gene polymorphisms and haplotypes with cervicitis susceptibility

A Chauhan, N Pandey, A Desai, N Raithatha, P Patel… - PLoS …, 2019 - journals.plos.org
Background Cervicitis is one of the major health problems amongst women caused by
infection of various pathogens including Chlamydia trachomatis (CT), Neisseria …