Background Beta‐blockers refer to a mixed group of drugs with diverse pharmacodynamic
and pharmacokinetic properties. They have shown long‐term beneficial effects on mortality …

Background This is the first update of a review published in 2010. While calcium channel
blockers (CCBs) are often recommended as a first‐line drug to treat hypertension, the effect …

Objective.—To assess the association between first myocardial infarction and the use of
antihypertensive agents. Design and Setting.—We conducted a population-based case …

This rapid update of the NICE guideline on hypertension in primary care was undertaken
because recent large clinical outcome trials had provided new information about the …

Essential hypertension is a major Public Health issue. Although the number of treated
hypertensive patients has increased, only 25% of treated patients have their blood pressure …

Hypertension is the most common, chronic disease in the world, and there are many
effective pharmacological agents available for its treatment. Despite the plethora of …

Abstract Background Certain immunoglobulins (Ig) are proposed to have protective
functions in atherosclerosis. Objectives We tested whether serum levels of IgG and IgM …

This study aimed to identify novel loci influencing the antihypertensive response to
hydrochlorothiazide monotherapy. A genome-wide meta-analysis of blood pressure (BP) …

Background The aim of the Nordic Diltiazem (NORDIL) Study was to compare patients with
essential hypertension receiving calcium-antagonist-based treatment with diltiazem and …

Objective: To analyse whether metabolic changes during long term treatment with
antihypertensive drugs are associated with an increased risk of coronary heart disease …