The colorful diversity of thyroid hormone metabolites

J Köhrle - European Thyroid Journal, 2019 - etj.bioscientifica.com
Since the discovery of L-thyroxine, the main secretory product of the thyroid gland, and its
major metabolite T3, which exerts the majority of thyroid hormone action via ligand …

[Retracted] Thyrotoxic Periodic Paralysis: Clinical Challenges

A Vijayakumar, G Ashwath… - Journal of thyroid …, 2014 - Wiley Online Library
Thyrotoxic periodic paralysis (TPP), a disorder most commonly seen in Asian men, is
characterized by abrupt onset of hypokalemia and paralysis. The condition primarily affects …

Guidelines for the treatment of hypothyroidism: prepared by the american thyroid association task force on thyroid hormone replacement

J Jonklaas, AC Bianco, AJ Bauer, KD Burman… - thyroid, 2014 - liebertpub.com
Background: A number of recent advances in our understanding of thyroid physiology may
shed light on why some patients feel unwell while taking levothyroxine monotherapy. The …

Thyrotoxic periodic paralysis: clinical and molecular aspects

H Falhammar, M Thorén, J Calissendorff - Endocrine, 2013 - Springer
Thyrotoxic periodic paralysis (TPP) is a rare complication of hyperthyroidism that most often
affects young East Asian males but increasingly also in other ethnic groups. The typical …

Neuro-nutraceuticals: The path to brain health via nourishment is not so distant

RJ Williams, KP Mohanakumar, PM Beart - Neurochemistry International, 2015 - Elsevier
Abstract In this Special Issue on “Nutraceuticals: Molecular and Functional Insights into how
Natural Products Nourish the Brain”, the editors bring together contributions from experts in …

Off-label use and misuse of testosterone, growth hormone, thyroid hormone, and adrenal supplements: risks and costs of a growing problem

MS Irwig, M Fleseriu, J Jonklaas, NA Tritos, KCJ Yuen… - Endocrine Practice, 2020 - Elsevier
Over the past few decades, there has been an unprecedented rise in off-label use and
misuse of testosterone, growth hormone, thyroid hormone, and adrenal supplements …

Triiodothyroacetic acid in health and disease

S Groeneweg, RP Peeters, TJ Visser… - Journal of …, 2017 - joe.bioscientifica.com
Thyroid hormone (TH) is crucial for development and metabolism of many tissues. The
physiological relevance and therapeutic potential of TH analogs have gained attention in the …

[HTML][HTML] Physiological role and use of thyroid hormone metabolites-potential utility in COVID-19 patients

E Fröhlich, R Wahl - Frontiers in endocrinology, 2021 - frontiersin.org
Thyroxine and triiodothyronine (T3) are classical thyroid hormones and with relatively well-
understood actions. In contrast, the physiological role of thyroid hormone metabolites, also …

Inhibition of the human hsc70 system by small ligands as a potential anticancer approach

L Dublang, J Underhaug, MI Flydal… - Cancers, 2021 - mdpi.com
Simple Summary High levels of Heat shock proteins (Hsps) in specific cancers are usually
linked to a poor prognosis, tumor progression, invasiveness, and resistance to treatment …

Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa

S Kitamura, KL Hvorecny, J Niu… - Journal of medicinal …, 2016 - ACS Publications
The virulence factor cystic fibrosis transmembrane conductance regulator (CFTR) inhibitory
factor (Cif) is secreted by Pseudomonas aeruginosa and is the founding member of a distinct …