Aneuploidy: Cancer strength or vulnerability?

G Simonetti, S Bruno, A Padella, E Tenti… - … journal of cancer, 2019 - Wiley Online Library
Aneuploidy is a very rare and tissue‐specific event in normal conditions, occurring in a low
number of brain and liver cells. Its frequency increases in age‐related disorders and is one …

Overexpression of BUB1B, CCNA2, CDC20, and CDK1 in tumor tissues predicts poor survival in pancreatic ductal adenocarcinoma

S Dong, F Huang, H Zhang, Q Chen - Bioscience reports, 2019 - portlandpress.com
Overexpressed genes in tumors usually contributed to aggressiveness in pancreatic ductal
adenocarcinoma (PDAC). Using Gene Expression Omnibus (GEO) profiles including …

[HTML][HTML] NEAT1 regulates pancreatic cancer cell growth, invasion and migration though mircroRNA-335-5p/c-met axis

J Cao, Y Zhang, J Yang, S He, M Li, S Yan… - American journal of …, 2016 - ncbi.nlm.nih.gov
NEAT1 has been reported to affect cancer progression, which was subsequently confirmed
in multiple cancers. Hsa-miRNA-335-5p (miR-335-5p) has recently been identified as an …

The clinical value and biological function of PTTG1 in colorectal cancer

Q Ren, B Jin - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Pituitary tumor transforming gene-1 (PTTG1) has been suggested to serve as an oncogene
in several types of human tumors, but little is known about the biological function of PTTG1 …

Evaluation of oncogene NUP37 as a potential novel biomarker in breast cancer

K Li, T Liu - Frontiers in oncology, 2021 - frontiersin.org
Purpose There is an urgent need to identify oncogenes that may be beneficial to diagnose
and develop target therapy for breast cancer. Methods Based on the GEO database …

Upregulation of ASPM, BUB1B and SPDL1 in tumor tissues predicts poor survival in patients with pancreatic ductal adenocarcinoma

X Tian, N Wang - Oncology Letters, 2020 - spandidos-publications.com
Pancreatic ductal adenocarcinoma (PDAC) remains a major cause of cancer‑associated
mortality, with poor patient outcome. The present study aimed to identify key candidate …

Bioinformatic analysis suggests that three hub genes may be a vital prognostic biomarker in pancreatic ductal adenocarcinoma

X Chang, MF Yang, W Fan, LS Wang, J Yao… - Journal of …, 2020 - liebertpub.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies worldwide
due to its ineffective diagnosis and poor prognosis. It is essential to identify differentially …

Identification of the lncRNA‑miRNA‑mRNA network associated with gastric cancer via integrated bioinformatics analysis

XY Ma, Y Ma, H Zhou, HJ Zhang… - Oncology …, 2019 - spandidos-publications.com
The aim of the present study was to investigate the long non‑coding RNA (lncRNA)‑
microRNA (miRNA)‑mRNA regulatory network in gastric cancer (GC) using bioinformatics …

Pituitary tumor transforming gene-1 in non-small cell lung cancer: clinicopathological and immunohistochemical analysis

F Wang, Y Liu, Y Chen - Biomedicine & Pharmacotherapy, 2016 - Elsevier
Pituitary tumor transforming gene-1 (PTTG1) is a novel oncogene and overexpressed in a
wide variety of human cancers. However, the clinical and prognostic significance of PTTG1 …

Identification of key regulators of pancreatic ductal adenocarcinoma using bioinformatics analysis of microarray data

N Li, X Zhao, S You - Medicine, 2019 - journals.lww.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal forms of cancer, and its
etiology remains largely unknown. This study aimed to screen a panel of key genes and to …