The genetics of Ewing sarcoma (ES) are characterized by a canonical fusion involving
EWSR1 gene and a member of the ETS family of transcription factors, such as FLI1 and …

The Hippo pathway is dysregulated in many different cancers, but point mutations in the
pathway are rare. Transcriptional co-activator with PDZ-binding motif (TAZ) and Yes …

Purpose: We undertook a multidimensional clinical genomics study of children and
adolescent young adults with relapsed and refractory cancers to determine the feasibility of …

Undifferentiated solid tumors with small blue round cell histology and expression of CD99
mostly resemble Ewing sarcoma. However, they also may include other tumors such as …

Abstract CIC-DUX4 and BCOR-CCNB3 fusion-gene-associated small round cell sarcomas
account for a proportion of pediatric small round cell sarcomas, but their pathological …

Ewing‐like sarcomas are an emerging subgroup of small round blue cell sarcomas that
share various degrees of morphological, immunohistochemical, molecular, and clinical …

Endometrial stromal sarcomas (ESS) are genetically heterogeneous uterine tumors in which
a JAZF1‐SUZ12 chimeric gene resulting from the chromosomal translocation t (7; 17)(p15; …

A subset of small round cell sarcomas remains difficult to classify. Among these, a rare tumor
harboring at (4; 19)(q35; q13. 1) with CIC-DUX4 fusion has been described. The aim of this …

Ewing sarcoma is an undifferentiated small-round-cell sarcoma. Although molecular
detection of pathognomonic EWSR1-ETS fusions such as EWSR1-FLI1 enables definitive …

Context.—Current 2013 World Health Organization classification of tumors of soft tissue
arranges these tumors into 12 groups according to their histogenesis. Tumor behavior is …