[HTML][HTML] Synthesis of temporin L hydroxamate-based peptides and evaluation of their coordination properties with iron (III)
Ferric iron is an essential nutrient for bacterial growth. Pathogenic bacteria synthesize iron-
chelating entities known as siderophores to sequestrate ferric iron from host organisms in …
chelating entities known as siderophores to sequestrate ferric iron from host organisms in …
Current developments and prospects of the antibiotic delivery systems
K Kharga, S Jha, T Vishwakarma… - Critical Reviews in …, 2024 - Taylor & Francis
Antibiotics have remained the cornerstone for the treatment of bacterial infections ever since
their discovery in the twentieth century. The uproar over antibiotic resistance among bacteria …
their discovery in the twentieth century. The uproar over antibiotic resistance among bacteria …
Antibody–Antibiotic Conjugates: A Comprehensive Review on Their Therapeutic Potentials Against BacterialInfections
A Darbandi, M Abdi, S Dashtbin… - Journal of Clinical …, 2024 - Wiley Online Library
Introduction Antibodies are significant agents in the immune system and have proven to be
effective in treating bacterial infections. With the advancement of antibody engineering in …
effective in treating bacterial infections. With the advancement of antibody engineering in …
Beyond antibiotics: Emerging antivirulence strategies to combat Pseudomonas aeruginosa in cystic fibrosis
Pseudomonas aeruginosa is an opportunistic pathogen that poses a significant threat to
individuals suffering from cystic fibrosis (CF). The pathogen is highly prevalent in CF …
individuals suffering from cystic fibrosis (CF). The pathogen is highly prevalent in CF …
Natural products from human microbiome: an emergent frontier in organic synthesis and drug discovery
G Mehta, S Sengupta, S Pabbaraja - Organic & Biomolecular …, 2024 - pubs.rsc.org
Often referred to as “second genome”, human microbiome is at the epicenter of a complex
inter-habitat biochemical network, such as the “gut-brain axis”, which have emerged as …
inter-habitat biochemical network, such as the “gut-brain axis”, which have emerged as …
[HTML][HTML] Exploring Fe (III) coordination and membrane interaction of a siderophore-peptide conjugate: Enhancing synergistically the antimicrobial activity
R Bellavita, S Braccia, LE Imbò, P Grieco… - Journal of Inorganic …, 2024 - Elsevier
Many microbes produce siderophores, which are extremely potent weapons capable of
stealing iron ions from human tissues, fluids and cells and transferring them into bacteria …
stealing iron ions from human tissues, fluids and cells and transferring them into bacteria …
Next-generation antibiotics, bacteriophage endolysins, and nanomaterials for combating pathogens
IG Shemyakin, VV Firstova, NK Fursova, IV Abaev… - Biochemistry …, 2020 - Springer
This review presents various strategies to fight causative agents of infectious diseases.
Species-specific programmable RNA-containing antibiotics open up new possibilities for …
Species-specific programmable RNA-containing antibiotics open up new possibilities for …
[HTML][HTML] In vitro and in silico studies of enterobactin-inspired Ciprofloxacin and Fosfomycin first generation conjugates on the antibiotic resistant E. coli OQ866153
MT Khazaal, AHI Faraag, HH El-Hendawy - BMC microbiology, 2024 - Springer
Background The emergence of antimicrobial resistance in bacterial pathogens is a growing
concern worldwide due to its impact on the treatment of bacterial infections. The" Trojan …
concern worldwide due to its impact on the treatment of bacterial infections. The" Trojan …
Design, synthesis, structure elucidation, antimicrobial, molecular docking, and SAR studies of novel urea derivatives bearing tricyclic aromatic hydrocarbon rings
The targeted compounds were prepared using both (9H‐fluoren‐9‐ylidene) hydrazine (1)
and 10H‐phenothiazine (2) as starting materials. The treatment of 1 or 2 with different …
and 10H‐phenothiazine (2) as starting materials. The treatment of 1 or 2 with different …
[HTML][HTML] Novel Hydroxamic Acids Containing Aryl-Substituted 1, 2, 4-or 1, 3, 4-Oxadiazole Backbones and an Investigation of Their Antibiotic Potentiation Activity
AA Zhukovets, VV Chernyshov… - International Journal of …, 2023 - mdpi.com
UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) is a zinc
amidase that catalyzes the second step of the biosynthesis of lipid A, which is an outer …
amidase that catalyzes the second step of the biosynthesis of lipid A, which is an outer …