Atherosclerosis and its clinical manifestations (ie myocardial infarction, stroke) are major
causes of mortality and morbidity in Western countries. Endothelial dysfunction is …

This is the first of three articles re-viewing presentations at the 3rd Annual World Congress
on the Insulin Resistance Syndrome, San Francisco, California, 17–19 November 2005 …

Estrogen and hormone replacement therapies are being tested to prevent the incidence of
cardiovascular disease in postmenopausal women. In spite of the evidence from several …

The effects of sphingosine 1-phosphate (S1P) on prostaglandin I2 (PGI2) production and
cyclooxygenase (COX) expression in cultured rat vascular smooth muscle cells (VSMCs) …

Atherosclerosis is currently understood to be mainly the consequence of a complicated
inflammatory process at the different stages of plaque development. Among the several …

Cyclooxygenase (COX) is the rate limiting enzyme catalyzing the conversion of arachidonic
acid into prostanoids, lipid mediators critically implicated in a variety of physiological and …

Aim/Purpose of the study: Inhibition of microglial activation using phytochemicals may be a
potential candidate for the prevention of neurodegenerative diseases caused by …

BACKGROUND:: The Losartan Intervention For End-point reduction in hypertension (LIFE)
study found that a losartan-based regimen, compared with an atenolol-based regimen …

The endothelium controls vascular tone by releasing various vasoactive substances.
Additionally, another pathway associated with the hyperpolarization of both endothelial and …

Antiplatelet therapy provided pivotal advances in the treatment of cardiovascular disease.
Aspirin and thienopyridine, clopidogrel, is currently the treatment of choice in acute coronary …