Is hepatitis E virus a neglected or emerging pathogen in Egypt?

IM Sayed, SF Abdelwahab - Pathogens, 2022 - mdpi.com
Though Egypt ranks among the top countries for viral hepatitis and death-related liver
disease, Hepatitis E virus (HEV) is a neglected pathogen. Living in villages and rural …

B cell–activating factor modulates the factor VIII immune response in hemophilia A

BS Doshi, J Rana, G Castaman… - The Journal of …, 2021 - Am Soc Clin Investig
Inhibitors of factor VIII (FVIII) remain the most challenging complication of FVIII protein
replacement therapy in hemophilia A (HA). Understanding the mechanisms that guide FVIII …

Characterization of virus‒host recombinant variants of the hepatitis E virus

O Paronetto, C Allioux, C Diméglio, L Lobjois… - Journal of …, 2024 - Am Soc Microbiol
Hepatitis E virus is a single-strand, positive-sense RNA virus that can lead to chronic
infection in immunocompromised patients. Virus–host recombinant variants (VHRVs) have …

Experimental trials of predicted CD4+ and CD8+ T-cell epitopes of respiratory syncytial virus

ST Qousain Naqvi, SA Muhammad, J Guo… - Frontiers in …, 2024 - frontiersin.org
Background Respiratory syncytial virus (RSV) is the most common cause of viral lower
respiratory tract infections (LRTIs) in young children around the world and an important …

Animal models for hepatitis E virus

T Liu, L Wang, L Wang - Hepatitis E Virus, 2023 - Springer
Animal models are one of the most important tools in the study of human hepatitis E virus
(HEV) infection. They are particularly important in light of the major limitations of the cell …

Establishment of an animal model of immune‐related adverse events induced by immune checkpoint inhibitors

Y Meng, Y Lv, M Shen, W Yu, Y Liu, T Liu… - Cancer …, 2024 - Wiley Online Library
Objective Immunotherapy, specifically immune checkpoint inhibitors (ICIs), has
revolutionized cancer treatment. However, it can also cause immune‐related adverse events …

Study of hepatitis E virus-4 infection in human liver-chimeric, immunodeficient, and immunocompetent mice

L Collignon, L Verhoye… - Frontiers in …, 2022 - frontiersin.org
The hepatitis E virus (HEV) is responsible for 20 million infections worldwide per year.
Although, HEV infection is mostly self-limiting, immunocompromised individuals may evolve …

Are ruminants and their products potential sources of human hepatitis E virus infection?

IM Sayed, MA El-Mokhtar - Future Virology, 2021 - Taylor & Francis
Conclusion Ruminants and/or products such as milk and liver are potential sources of HEV
infection. Ingestion of raw milk products and undercooked liver products is a risk factor for …

Hepatitis E virus infection upregulates ING5 expression in vitro and vivo

W Zhao, Y Xia, T Li, H Liu, G Zhong, D Chen, W Yu… - bioRxiv, 2024 - biorxiv.org
Hepatitis E virus (HEV) is the major pathogen of viral hepatitis. Immunocompromised
individual infected by HEV is prone to chronic hepatitis and increases the risk of hepato …

Animal Models for Hepatitis E Virus 12

T Liu, L Wang, L Wang - Hepatitis E Virus - Springer
Animal models are one of the most important tools in the study of human hepatitis E virus
(HEV) infection. They are particularly important in light of the major limitations of the cell …