Barriers and facilitators of implementing proactive deprescribing within primary care: a systematic review

DA Okeowo, STR Zaidi, B Fylan… - International Journal of …, 2023 - academic.oup.com
Objective Proactive deprescribing–identifying and discontinuing medicines where harms
outweigh benefits–can minimise problematic polypharmacy, but has yet to be implemented …

Health care professional barriers and facilitators to discontinuing antidepressant use: A systematic review and thematic synthesis

E Van Leeuwen, E Maund, C Woods, H Bowers… - Journal of Affective …, 2024 - Elsevier
Introduction Long-term antidepressant (AD) use, much longer than recommended, is very
common and can lead to potential harms. Objective To investigate the existing literature on …

'Never change a winning team': GPs' perspectives on discontinuation of long-term antidepressants

S Anthierens, ML van Driel, AD Sutter… - … Journal of Primary …, 2021 - Taylor & Francis
Background Long-term antidepressant use, much longer than recommended by guidelines,
can harm patients and generate unnecessary costs. Most antidepressants are prescribed by …

Discontinuation of antidepressant treatment: a retrospective cohort study on more than 20,000 participants

LM Garcia-Marin, A Mulcahy, EM Byrne… - Annals of General …, 2023 - Springer
Background Factors influencing antidepressant treatment discontinuation are poorly
understood. In the present study, we aimed to estimate the prevalence of antidepressant …

Antidepressant medication prescribing patterns in Irish general practice from 2016 to 2020 to assess for long-term use

A McCool, K Lukas, P Hayes, D Kelly - Irish Journal of Medical Science …, 2021 - Springer
Background/aims The aim of this study was to identify the trends in antidepressant (AD)
medication use in two Irish general practices over a 5-year period, 2016 to 2020. The …

RELEASE (REdressing Long-tErm Antidepressant uSE): protocol for a 3-arm pragmatic cluster randomised controlled trial effectiveness-implementation hybrid type-1 …

KA Wallis, M Donald, M Horowitz, J Moncrieff, RS Ware… - Trials, 2023 - Springer
Background Many people experience withdrawal symptoms when they attempt to stop
antidepressants. Withdrawal symptoms are readily misconstrued for relapse or ongoing …

Acceptability and optimisation of resources to support antidepressant cessation: a qualitative think-aloud study with patients in Australian primary care

S McDonald, K Wallis, M Horowitz, E Mann, V Le… - British Journal of …, 2024 - bjgp.org
Background Stopping long-term (> 12 months) antidepressant use can be difficult due to
unpleasant withdrawal symptoms. Many people do not recognise withdrawal symptoms or …

Should I, can I, dare I? Patients' view on stopping long-term antidepressant use, a qualitative study

E Van Leeuwen, S Anthierens, ML van Driel… - Acta Clinica …, 2022 - Taylor & Francis
Background and aim The rise in long-term antidepressant use is concerning. Long-term
antidepressant (AD) use, much longer than recommended by guidelines, can result in risk of …

Antidepressant prescribing in general practice:'A call to action'

KA Wallis, M Donald, J Moncrieff - Australian Journal of General …, 2021 - search.informit.org
The'Mental health: Productivity Commission Inquiry Report'(2020) recommended as
a'priority reform'that we'[a] ddress adverse outcomes from prescribing practices of mental …

Examining clinician choice to follow-up (or not) on automated notifications of medication non-adherence by clinical decision support systems

D Thorpe, J Strobel, N Bidargaddi - BMC Medical Informatics and Decision …, 2023 - Springer
Background Maintaining medication adherence can be challenging for people living with
mental ill-health. Clinical decision support systems (CDSS) based on automated detection of …