An autoimmune disease is defined as a clinical syndrome resulted from an instigation of
both T cell and B cell or individually, in the absence of any present infection or any sort of …

Advances in our understanding of the structure and function of the lymphatic system have
made it possible to identify its role in a variety of disease processes. Because it is involved …

Most forms of arthritis are incurable, difficult to treat, and a major cause of disability in
Western countries. Better local treatment of arthritis is impaired by the pharmacokinetics of …

Although clinical outcomes for patients with rheumatoid arthritis (RA) have greatly improved
with the use of biologic and conventional DMARDs, approximately 40% of patients do not …

Objective. Subclinical synovitis can be detected by ultrasound in patients with rheumatoid
arthritis (RA) who are in clinical remission. We aimed to confirm its predictive value for flare …

Lymphatic vessel networks are a main part of the vertebrate cardiovascular system, which
participate in various physiological and pathological processes via regulation of fluid …

Lymphangiogenesis is a recognized hallmark of inflammatory processes in tissues and
organs as diverse as the skin, heart, bowel, and airways. In clinical and animal models …

Background In this study, we sought to determine the cellular source of inducible nitric oxide
synthase (iNOS) induced in lymphatic endothelial cells (LECs) in response to tumor necrosis …

Rheumatoid arthritis (RA), as an autoimmune inflammatory disease, is featured by
enhanced vascular permeability, irreversible cartilage destroys and bone erosion. Although …

The lymphatics play important roles in chronic diseases/conditions that comprise the bulk of
healthcare worldwide. Yet the ability to routinely image and diagnose lymphatic dysfunction …