Acquired haemophilia A: a review of what we know
ME Mingot-Castellano… - Journal of Blood …, 2022 - Taylor & Francis
Autoantibodies against plasma coagulation factors could be developed by some individuals
inducing severe and sometimes fatal bleedings. This clinical entity is called acquired …
inducing severe and sometimes fatal bleedings. This clinical entity is called acquired …
Emicizumab for the treatment of acquired hemophilia A
P Knoebl, J Thaler, P Jilma… - Blood, The Journal …, 2021 - ashpublications.org
Acquired hemophilia A (AHA) is a severe bleeding disorder caused by inhibiting
autoantibodies to coagulation factor VIII (FVIII). For hemostatic treatment, bypassing agents …
autoantibodies to coagulation factor VIII (FVIII). For hemostatic treatment, bypassing agents …
[HTML][HTML] A prospective, multicenter, open-label phase III study of emicizumab prophylaxis in patients with acquired hemophilia A
M Shima, K Amano, Y Ogawa, K Yoneyama… - Journal of Thrombosis …, 2023 - Elsevier
Background Emicizumab is a bispecific antibody that mimics the cofactor function of
activated factor (F) VIII. It prevents bleeds in patients with congenital hemophilia A …
activated factor (F) VIII. It prevents bleeds in patients with congenital hemophilia A …
[HTML][HTML] New developments in diagnosis and management of acquired hemophilia and acquired von Willebrand Syndrome
FWG Leebeek - HemaSphere, 2021 - journals.lww.com
Acquired hemophilia A and acquired von Willebrand syndrome are rare, but life-threatening
bleeding disorders that require prompt diagnosis and treatment by hematologists. Acquired …
bleeding disorders that require prompt diagnosis and treatment by hematologists. Acquired …
Combined immunosuppression for acquired hemophilia A: CyDRi is a highly effective low-toxicity regimen
B Simon, A Ceglédi, J Dolgos, P Farkas… - Blood, The Journal …, 2022 - ashpublications.org
Acquired hemophilia A (AHA) is a rare severe autoimmune bleeding disorder with significant
morbidity and mortality. Although critical for disease control, there is no consensus for the …
morbidity and mortality. Although critical for disease control, there is no consensus for the …
[HTML][HTML] Should emicizumab be used in patients with acquired hemophilia A?
A Tiede, B Kemkes-Matthes, P Knöbl - Journal of Thrombosis and …, 2021 - Elsevier
Emicizumab is currently approved to prevent bleeding in patients with congenital hemophilia
A with or without neutralizing antibodies (inhibitors) against factor VIII (FVIII). Here, we …
A with or without neutralizing antibodies (inhibitors) against factor VIII (FVIII). Here, we …
Emicizumab prophylaxis in patients with acquired haemophilia A (GTH-AHA-EMI): an open-label, single-arm, multicentre, phase 2 study
A Tiede, C Hart, P Knöbl, R Greil… - The Lancet …, 2023 - thelancet.com
Background Acquired haemophilia A is caused by neutralising autoantibodies against
coagulation factor VIII, leading to severe bleeding. Standard treatment involves …
coagulation factor VIII, leading to severe bleeding. Standard treatment involves …
Acquired haemophilia A in the postpartum and risk of relapse in subsequent pregnancies: a systematic literature review
N Dewarrat, M Gavillet, A Angelillo‐Scherrer… - …, 2021 - Wiley Online Library
Abstract Background About 1%–5% of acquired haemophilia A cases affect mothers in the
postpartum setting. Aims This study delineates the characteristics of this disease, specific to …
postpartum setting. Aims This study delineates the characteristics of this disease, specific to …
[HTML][HTML] Unexplained hemorrhagic syndrome? Consider acquired hemophilia A or B
There is a dire need to develop an algorithm to improve the recognition of acquired
hemophilia A and B (AHA and AHB) in clinical practice. Initial and intensive care unit (ICU) …
hemophilia A and B (AHA and AHB) in clinical practice. Initial and intensive care unit (ICU) …
[PDF][PDF] The rising incidence of acquired haemophilia A in Germany
A Tiede, S Wahler - Haemophilia, 2021 - researchgate.net
Acquired hemophilia A (AHA) is a rare autoimmune disorder resulting from the formation of
neutralizing antibodies against coagulation factor VIII (FVIII). 1, 2 It is characterized by a …
neutralizing antibodies against coagulation factor VIII (FVIII). 1, 2 It is characterized by a …