Trypanosoma cruzi is the etiological agent of Chagas disease. The life cycle of this
protozoan parasite is digenetic because it alternates its different developmental forms …

Chagas disease is caused by the Trypanosoma cruzi affecting millions of people, and
widespread throughout Latin America. This disease exhibits a problematic chemotherapy …

Chagas disease is a chronic systemic infection transmitted by Trypanosoma cruzi. Its life
cycle consists of different stages in vector insects and host mammals. Trypanosoma cruzi …

Background Chagas disease is the third most important neglected tropical disease. There is
no vaccine available, and only two drugs are generally prescribed for the treatment, both of …

Breast cancer is the most common type of cancer and the leading cause of cancer mortality
among women worldwide. Considering the limitations of the current treatments available, we …

Abstract Two 1, 5-diaryl-3-oxo-1, 4-pentadienyls (1 and 2) having nitro group attached
exhibited potent anti-parasitic activity when evaluated against Trypanosoma cruzi and …

Unsymmetrical diarylpentanoid analogues of curcumin have been synthesized by Claisen–
Schmidt condensation of different aldehydes and ketones. Anisaldehyde treated with 2 …

In this review we refer to a promising family of molecules in the fight against Chagas
disease. Terpene derivatives are abundant in the plant Kingdom and in the last years many …

Background: Cutaneous leishmaniasis is caused by Leishmania spp., and its treatment is
limited. The β-carbolines have shown activity against kinetoplastids. Aim: To evaluate the …

New antiviral agents for the treatment of herpes simplex virus type 1 (HSV-1) infection, which
causes a highly prevalent and incurable disease, are needed. Here, we report for the first …