Switching from high-fat diet to normal diet ameliorate BTB integrity and improve fertility potential in obese male mice
W Zhang, Z Tian, X Qi, P Chen, Q Yang, Q Guan… - Scientific Reports, 2023 - nature.com
Obesity is a prominent risk factor for male infertility, and a high-fat diet is an important cause
of obesity. Therefore, diet control can reduce body weight and regulate blood glucose and …
of obesity. Therefore, diet control can reduce body weight and regulate blood glucose and …
[HTML][HTML] Paternal diet-induced obesity impairs embryo development and implantation in the mouse
OBJECTIVE: To use a rodent model of male diet-induced obesity (DIO) to examine resultant
preimplantation embryo development and implantation rate, as well as fetal and placental …
preimplantation embryo development and implantation rate, as well as fetal and placental …
High‐fat diets reduce male reproductive success in animal models: A systematic review and meta‐analysis
Sperm counts have shown a progressive decline across the world since the mid‐1900s.
Global rates of obesity have been climbing at a similarly alarming rate, suggesting that these …
Global rates of obesity have been climbing at a similarly alarming rate, suggesting that these …
Oxidative stress in mouse sperm impairs embryo development, fetal growth and alters adiposity and glucose regulation in female offspring
Paternal health cues are able to program the health of the next generation however the
mechanism for this transmission is unknown. Reactive oxygen species (ROS) are increased …
mechanism for this transmission is unknown. Reactive oxygen species (ROS) are increased …
Impact of obesity and overweight on DNA stability: Few facts and many hypotheses
T Setayesh, A Nersesyan, M Mišík, F Ferk… - … research/reviews in …, 2018 - Elsevier
Health authorities are alarmed worldwide about the increase of obesity and overweight in
the last decades which lead to adverse health effects including inflammation, cancer …
the last decades which lead to adverse health effects including inflammation, cancer …
Paternal diet-induced obesity retards early mouse embryo development, mitochondrial activity and pregnancy health
Worldwide, 48% of adult males are overweight or obese. An association between infertility
and excessive body weight is now accepted, although focus remains primarily on females. It …
and excessive body weight is now accepted, although focus remains primarily on females. It …
The effect of excess body fat on female and male reproduction
The dramatic increase in the prevalence of obesity coincides with a decline in reproductive
health indices in both sexes. Energy excess mediates changes to the regulatory …
health indices in both sexes. Energy excess mediates changes to the regulatory …
Paternal high‐fat diet consumption induces common changes in the transcriptomes of retroperitoneal adipose and pancreatic islet tissues in female rat offspring
We previously showed that paternal high‐fat diet (HFD) consumption programs β‐cell
dysfunction in female rat offspring, together with transcriptome alterations in islets. Here we …
dysfunction in female rat offspring, together with transcriptome alterations in islets. Here we …
Obesity, energy balance and spermatogenesis
Obesity has grown to pandemic proportions. It affects an increasing number of children,
adolescents and young adults exposed to the silent comorbidities of this disorder for a …
adolescents and young adults exposed to the silent comorbidities of this disorder for a …
Metformin improves fertility in obese males by alleviating oxidative stress‐induced blood‐testis barrier damage
J Ye, D Luo, X Xu, M Sun, X Su, Z Tian… - Oxidative medicine …, 2019 - Wiley Online Library
Background/Aims. Obesity, which is related to increased oxidative stress in various tissues,
is a risk factor for male infertility. Metformin is reported to have an antioxidant effect; …
is a risk factor for male infertility. Metformin is reported to have an antioxidant effect; …