Transporters influence the disposition of chemicals within the body by participating in
absorption, distribution, and elimination. Transporters of the solute carrier family (SLC) …

nitrofurans (NFs) have been in clinical use for over 60 years. These affordable drugs are
used for the treatment of a broad spectrum of diseases ranging from urinary tract infections …

Nitrofurantoin is a commonly used urinary tract antibiotic prescribed to lactating woman. It is
actively transported into human and rat milk by an unknown mechanism. Our group has …

The breast cancer resistance protein [BCRP (also known as ABCG2)] belongs to the ATP
binding cassette (ABC) family of transmembrane drug transporters. BCRP has a broad …

Breastfeeding is the optimal form of infant feeding for the first months of an infant's life, and
the majority of healthy women initiate breastfeeding after the birth of their infant. However …

Transporter-mediated processes in the lactating mammary gland may explain the significant
accumulation of certain drugs in breast milk. The purpose of this study was to identify …

Co-amorphous drug delivery systems based on amino acids as co-formers have shown
promising potential to improve the solubility and bioavailability of poorly water-soluble …

The discovery and characterization of breast cancer resistance protein (BCRP) as an efflux
transporter conferring multidrug resistance has set off a remarkable trajectory in the …

Although most medications can be taken safely during breastfeeding, potential risks of infant
toxicity do exist because all medications will be excreted into the breast milk to some extent …

Multiple Sclerosis (MS) is an autoimmune neurological disease characterized by
inflammation of the brain and spinal cord. Relapsing‐Remitting MS is characterized by acute …