Pathogenic fungi have emerged as significant causes of infectious morbidity and death in
patients with acquired immunodeficiency conditions such as HIV/AIDS and following receipt …

The respiratory tree maintains sterilizing immunity against human fungal pathogens.
Humans inhale ubiquitous filamentous molds and geographically restricted dimorphic fungal …

Vaccines are one of the most effective public health tools to prevent and manage infectious
diseases. Since the first clinical use of vaccines in the late 18th century, many vaccines have …

Systemic cryptococcosis is fatal without treatment. Even with the current antifungal therapies,
this disease kills 180,000 of 225,000 infected people annually. Exposure to the causative …

The detrimental impact of fungal infections to human health has steadily increased over the
past decades. In October of 2022, the World Health Organization published the first ever …

In previous studies, we determined that the F-box protein Fbp1, a subunit of the SCF (Fbp1)
E3 ligase in Cryptococcus neoformans, is essential for fungal pathogenesis. Heat-killed …

Cryptococcus neoformans is an encapsulated pathogenic fungus that initially infects the
lung but can migrate to the central nervous system (CNS), resulting in meningoencephalitis …

The increasing global food scarcity necessitates the development of nanomaterials with low
toxicity for use as antimicrobial agents and sensors to mitigate agricultural losses. In this …

The development of efficient fungal vaccines is urgent for preventing life-threatening
systemic fungal infections. In this study, we prepared a synthetic, cell-based fungal vaccine …

Cryptococcus neoformans is a widely distributed opportunistic pathogenic fungus. While C.
neoformans commonly infects immunocompromised individuals, it can also affect those who …