Programming of neural cells by (endo) cannabinoids: from physiological rules to emerging therapies
M Maccarrone, M Guzmán, K Mackie… - Nature Reviews …, 2014 - nature.com
Among the many signalling lipids, endocannabinoids are increasingly recognized for their
important roles in neuronal and glial development. Recent experimental evidence suggests …
important roles in neuronal and glial development. Recent experimental evidence suggests …
The role of cannabinoids in adult neurogenesis
JA Prenderville, ÁM Kelly… - British journal of …, 2015 - Wiley Online Library
The processes underpinning post‐developmental neurogenesis in the mammalian brain
continue to be defined. Such processes involve the proliferation of neural stem cells and …
continue to be defined. Such processes involve the proliferation of neural stem cells and …
Microglia actively remodel adult hippocampal neurogenesis through the phagocytosis secretome
I Diaz-Aparicio, I Paris, V Sierra-Torre… - Journal of …, 2020 - Soc Neuroscience
During adult hippocampal neurogenesis, most newborn cells undergo apoptosis and are
rapidly phagocytosed by resident microglia to prevent the spillover of intracellular contents …
rapidly phagocytosed by resident microglia to prevent the spillover of intracellular contents …
Modeling Rett syndrome with human patient-specific forebrain organoids
Engineering brain organoids from human induced pluripotent stem cells (hiPSCs) is a
powerful tool for modeling brain development and neurological disorders. Rett syndrome …
powerful tool for modeling brain development and neurological disorders. Rett syndrome …
Geotemporospatial and causal inference epidemiological analysis of US survey and overview of cannabis, cannabidiol and cannabinoid genotoxicity in relation to …
AS Reece, GK Hulse - BMC pediatrics, 2022 - Springer
Background Cannabinoids including cannabidiol have recognized genotoxic activities but
their significance has not been studied broadly epidemiologically across the teratological …
their significance has not been studied broadly epidemiologically across the teratological …
Quality of life and a surveillant endocannabinoid system
RA de Melo Reis, AR Isaac, HR Freitas… - Frontiers in …, 2021 - frontiersin.org
The endocannabinoid system (ECS) is an important brain modulatory network. ECS
regulates brain homeostasis throughout development, from progenitor fate decision to neuro …
regulates brain homeostasis throughout development, from progenitor fate decision to neuro …
Brain-derived neurotrophic factor (BDNF) role in cannabinoid-mediated neurogenesis
FF Ferreira, FF Ribeiro, RS Rodrigues… - Frontiers in cellular …, 2018 - frontiersin.org
The adult mammalian brain can produce new neurons in a process called adult
neurogenesis, which occurs mainly in the subventricular zone (SVZ) and in the hippocampal …
neurogenesis, which occurs mainly in the subventricular zone (SVZ) and in the hippocampal …
Cell calcium imaging as a reliable method to study neuron–glial circuits
RA de Melo Reis, HR Freitas… - Frontiers in neuroscience, 2020 - frontiersin.org
Complex dynamic cellular networks have been studied in physiological and pathological
processes under the light of single-cell calcium imaging (SCCI), a method that correlates …
processes under the light of single-cell calcium imaging (SCCI), a method that correlates …
Cannabis: a treasure trove or pandora's box?
K Solymosi, A Köfalvi - Mini reviews in medicinal chemistry, 2017 - ingentaconnect.com
Background & Objective: Cannabis is one of the earliest cultivated plants. Cannabis of
industrial utility and culinary value is generally termed as hemp. Conversely, cannabis that is …
industrial utility and culinary value is generally termed as hemp. Conversely, cannabis that is …
The Notch pathway in CNS homeostasis and neurodegeneration
DM Ho, S Artavanis‐Tsakonas… - Wiley Interdisciplinary …, 2020 - Wiley Online Library
The role of the Notch signaling pathway in neural development has been well established
over many years. More recent studies, however, have demonstrated that Notch continues to …
over many years. More recent studies, however, have demonstrated that Notch continues to …