The effect of adding divalent ions on the deoxyribonucleic acid (DNA) adsorption by a
cationic lipid monolayer at the air–water interface was investigated by X-ray reflectivity on …

Delivery of genetic substance to target cells remains an obstacle for efficient utilization of
gene therapy approaches. In this study, we describe a formulation of methacrylate acid …

Nos últimos anos, avanços no estudo do genoma e proteoma humano têm fornecido
informações essenciais em relação ao funcionamento correto dos genes e ao impacto das …

Abstract miR-122, the most abundant liver-specific microRNA (miRNA), is involved in many
different biological functions, including cholesterol metabolism, hepatitis C virus replication …

Gene transfer strategies are being tested in a variety of animal models for psychiatric
disorders. These promise to translate viral-mediated, non-viral and combinatorial techniques …

The field of medicine, this year, has been marked by the award of the Nobel Prize for
Chemistry to Emmanuelle Charpentier and Jennifer Doudna 'for the development of a …

BACKGROUND Transposons are discrete segments of DNA that have the distinctive ability
to move and replicate within genomes. Transposons were discovered in the 1940's by …

When instability of the lumbar spine causes persistent pain or neurological impairment, it is
usually treated by spinal fusion. Unfortunately, despite the development of spinal …

The present invention relates to a method of producing a polyomavirus or polyomavirus-
derived virus-like particle (vlp) carrying on its surface at least one targeting molecule that …

Zur Bekämpfung von genetisch bedingten Krankheiten werden oft Medikamente eingesetzt,
die nur die Symptome bekämpfen, ohne aber die Ursache des Leidens zu eliminieren. Mit …