Early embryonic arrest (EEA) is a critical impediment in assisted reproductive technology
(ART), affecting 40% of infertile patients by halting the development of early embryos from …

Several reports have presented that balanced chromosomal rearrangements (BCRs)
carriers with normal phenotypes may be carriers of complex rearrangements. However, the …

Background Optical genome mapping (OGM) has developed into a highly promising method
for detecting structural variants (SVs) in human genomes. Complex chromosomal …

Purpose To report genetic characteristics and associated risk of chromosomal breaks due to
chromosomal rearrangements in large samples. Methods MicroSeq, a technique that …

Naturally occurring balanced, unbalanced, and complex chromosomal rearrangements
have been reported to cause pathogenic genomic or genetic variants leading to infertility …

Currently, routine genetic investigation for male infertility includes karyotyping analysis and
PCR for Y chromosomal microdeletions to provide prognostic information such as sperm …

Male infertility is a multifactorial reproductive disorder. The effect of genetic factors on male
infertility has been the focus of research. Although a variety of genetic techniques are …

With the advancement of molecular technologies, conventional cytogenetics has been
transited successfully to an era of cytogenomics for the investigation of human genetic …

With the widespread use of antibiotics, bacterial infection-related morbidity and mortality
have significantly declined, revolutionizing modern medicine. However, concerns have been …

INVITED EDITORIAL intraflagellar transport protein 25 (IFT25) and its interactions with other
IFT particle subunits during flagellogenesis. Genetic defects also affect sperm head. After …