[HTML][HTML] Meeting at the crossroad between obesity and hepatic carcinogenesis: unique pathophysiological pathways raise expectations for innovative therapeutic …

K Arvanitakis, SP Papadakos, V Lekakis… - International Journal of …, 2023 - mdpi.com
The escalating global prevalence of obesity and its intricate association with the
development of hepatocellular carcinoma (HCC) pose a substantial challenge to public …

[HTML][HTML] Interplay of Extracellular Vesicles and TLR4 Signaling in Hepatocellular Carcinoma Pathophysiology and Therapeutics

SP Papadakos, K Arvanitakis, IE Stergiou, C Vallilas… - Pharmaceutics, 2023 - mdpi.com
Hepatocellular carcinoma (HCC) stands as a significant contributor to global cancer-related
mortality. Chronic inflammation, often arising from diverse sources such as viral hepatitis …

[HTML][HTML] γδ T Cells: A Game Changer in the Future of Hepatocellular Carcinoma Immunotherapy

SP Papadakos, K Arvanitakis, IE Stergiou… - International journal of …, 2024 - mdpi.com
Hepatocellular carcinoma (HCC) remains a global health challenge with limited treatment
options and a poor prognosis for advanced-stage patients. Recent advancements in cancer …

Crosstalk between Epigenetics and Metabolic Reprogramming in Metabolic Dysfunction-Associated Steatotic Liver Disease-Induced Hepatocellular Carcinoma: A …

A Li, R Wang, Y Zhao, P Zhao, J Yang - Metabolites, 2024 - mdpi.com
Epigenetic and metabolic reprogramming alterations are two important features of tumors,
and their reversible, spatial, and temporal regulation is a distinctive hallmark of …

[PDF][PDF] Meeting at the Crossroad between Obesity and Hepatic Carcinogenesis

K Arvanitakis, SP Papadakos, V Lekakis, T Koufakis… - 2023 - research.birmingham.ac.uk
The escalating global prevalence of obesity and its intricate association with the
development of hepatocellular carcinoma (HCC) pose a substantial challenge to public …