Genome-wide association studies in cancer have already identified over 150 regions
associated with two dozen specific cancers. Already, a handful of multi-cancer susceptibility …

The management of neuroendocrine neoplasia remains a perplexing problem because of
the lack of knowledge of the biology of the disease, its late presentation, the relative …

Early detection and definitive treatment of cancer have been shown to decrease death and
suffering in epidemiologic and intervention studies. Application of genomic approaches to …

Background: Controversy exists on whether urinary tract infection (UTI) is a risk factor for
urinary bladder cancer (UBC). Here, the association is investigated using data from one of …

We conducted a meta-analysis of three endometrial cancer genome-wide association
studies (GWAS) and two follow-up phases totaling 7,737 endometrial cancer cases and …

White blood cell (WBC) count is a common clinical measure from complete blood count
assays, and it varies widely among healthy individuals. Total WBC count and its constituent …

Coffee is the most commonly used stimulant and caffeine is its main psychoactive ingredient.
The heritability of coffee consumption has been estimated at around 50%. We performed a …

Thousands of noncoding somatic single-nucleotide variants (SNVs) of unknown function are
reported in tumors. Partitioning the genome according to cistromes reveals the enrichment of …

Background Metastasis have considered as an important clinical obstacle in the treatment of
human cancer including bladder cancer. Post-transcriptional regulation has emerged as …

The identification of accurate harbingers of disease status and therapeutic efficacy are
critical requirements in precise diagnosis and effective management. Initially, tissue analysis …