Iron supplementation therapy, a friend and foe of mycobacterial infections?

R Agoro, C Mura - Pharmaceuticals, 2019 - mdpi.com
Iron is an essential element that is required for oxygen transfer, redox, and metabolic
activities in mammals and bacteria. Mycobacteria, some of the most prevalent infectious …

The role of host genetics (and genomics) in tuberculosis

V Naranbhai - Microbiology Spectrum, 2016 - Am Soc Microbiol
Familial risk of tuberculosis (TB) has been recognized for centuries. Largely through studies
of mono-and dizygotic twin concordance rates, studies of families with Mendelian …

[HTML][HTML] Polymorphisms of SLC11A1 (NRAMP1) rs17235409 associated with and susceptibility to spinal tuberculosis in a southern Han Chinese population

T Li, L Wang, C Guo, H Zhang, P Xu, S Liu, X Hu… - Infection, Genetics and …, 2022 - Elsevier
Objective To investigate the association between SLC11A1 (NRAMP1) rs17235409
(D543N) polymorphisms and susceptibility to spinal tuberculosis (STB) in the Han …

[HTML][HTML] Effect of breastfeeding on children's health and its relationship to NRAMP1 expression: A cross-sectional study

MN Massi, ADB Febriani, M Hatta… - Annals of Medicine and …, 2021 - Elsevier
Toddlers with exclusive breastfeeding can increase immunity in preventing infectious
diseases such as Upper Respiratory Tract Infections (ARI). The body's resistance to disease …

NRAMP1 and VDR gene polymorphisms in susceptibility to pulmonary tuberculosis among Andhra Pradesh population in India: a case–control study

RV Medapati, S Suvvari, S Godi, P Gangisetti - BMC pulmonary medicine, 2017 - Springer
Background The aim of the present study was to evaluate the association of NRAMP1-3′
UTR, 274-CT, VDR-Fok1 VDR-Taq1 Polymorphisms with the risk of pulmonary tuberculosis …

FokI polymorphism of the vitamin D receptor (VDR) gene and susceptibility to tuberculosis: Evidence through a meta-analysis

U Yadav, P Kumar, V Rai - Infection, Genetics and Evolution, 2021 - Elsevier
Background Tuberculosis is one of the top ten causes of deaths worldwide. The deficiency of
vitamin D was reported to be associated with the increased susceptibility of tuberculosis …

Serum iron levels in tuberculosis patients and household contacts and its association with natural resistance‐associated macrophage protein 1 polymorphism and …

W Waworuntu, FS Tanoerahardjo… - The Clinical …, 2023 - Wiley Online Library
Background Iron deficiency can impair immune function, increasing tuberculosis (TB)
susceptibility and severity. The research aimed to investigate iron deficiency anemia in TB …

An updated trial sequential meta-analysis of vitamin D receptor gene polymorphism (FOK1, BSM1, TAQ1 and APA1) and risk to tuberculosis

S Shah, Priyanka, S Sharma - Indian Journal of Clinical Biochemistry, 2024 - Springer
Vitamin D receptor (VDR) is one of the most widely studied genes for the Tuberculosis (TB)
susceptibility. Several studies have been conducted to establish some association between …

Differential NRAMP1gene's D543N genotype frequency: Increased risk of contracting tuberculosis among Venezuelan populations

Z Araujo, M Camargo, DAM Pérez, A Wide… - Human Immunology, 2023 - Elsevier
NRAMP1 and VDR gene polymorphisms have been variably associated with susceptibility
to tuberculosis (TB) amongst populations having different genetic background. NRAMP1 …

[HTML][HTML] Early clearance versus control: what is the meaning of a negative tuberculin skin test or interferon-gamma release assay following exposure to Mycobacterium …

EW Meermeier, DM Lewinsohn - F1000Research, 2018 - ncbi.nlm.nih.gov
The elimination of tuberculosis (TB) cannot reasonably be achieved by treatment of
individual cases and will require an improved vaccine or immunotherapy. A challenge in …