Immunological memory to SARS‐CoV‐2 infection and COVID‐19 vaccines
Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …
previous infections. Immunological memory can develop from multiple branches of the …
T cell responses to SARS-CoV-2
A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …
[HTML][HTML] Mucosal vaccines for SARS-CoV-2: scientific gaps and opportunities—workshop report
JM Knisely, LE Buyon, R Mandt, R Farkas… - npj Vaccines, 2023 - nature.com
On November 7th and 8th, 2022, The National Institute of Allergy and Infectious Diseases
(NIAID), part of the National Institutes of Health (NIH), The Coalition for Epidemic …
(NIAID), part of the National Institutes of Health (NIH), The Coalition for Epidemic …
[HTML][HTML] Immune correlates analysis of the ENSEMBLE single Ad26. COV2. S dose vaccine efficacy clinical trial
Measuring immune correlates of disease acquisition and protection in the context of a
clinical trial is a prerequisite for improved vaccine design. We analysed binding and …
clinical trial is a prerequisite for improved vaccine design. We analysed binding and …
[HTML][HTML] Immune correlates analysis of the PREVENT-19 COVID-19 vaccine efficacy clinical trial
In the PREVENT-19 phase 3 trial of the NVX-CoV2373 vaccine (NCT04611802), anti-spike
binding IgG concentration (spike IgG), anti-RBD binding IgG concentration (RBD IgG), and …
binding IgG concentration (spike IgG), anti-RBD binding IgG concentration (RBD IgG), and …
[HTML][HTML] Impact of aging on immunity in the context of COVID-19, HIV, and tuberculosis
Knowledge of aging biology needs to be expanded due to the continuously growing number
of elderly people worldwide. Aging induces changes that affect all systems of the body. The …
of elderly people worldwide. Aging induces changes that affect all systems of the body. The …
[HTML][HTML] A critical analysis of the use of cilgavimab plus tixagevimab monoclonal antibody cocktail (Evusheld™) for COVID-19 prophylaxis and treatment
D Focosi, A Casadevall - Viruses, 2022 - mdpi.com
Evusheld®(tixagevimab+ cilgavimab; AZD7442) was the first anti-Spike monoclonal
antibody (mAb) cocktail designed not only for treatment but also with pre-exposure …
antibody (mAb) cocktail designed not only for treatment but also with pre-exposure …
[HTML][HTML] A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates
While the rapid development of COVID-19 vaccines has been a scientific triumph, the need
remains for a globally available vaccine that provides longer-lasting immunity against …
remains for a globally available vaccine that provides longer-lasting immunity against …
[HTML][HTML] Correlates of protection for booster doses of the SARS-CoV-2 vaccine BNT162b2
T Hertz, S Levy, D Ostrovsky, H Oppenheimer… - Nature …, 2023 - nature.com
Vaccination, especially with multiple doses, provides substantial population-level protection
against COVID-19, but emerging variants of concern (VOC) and waning immunity represent …
against COVID-19, but emerging variants of concern (VOC) and waning immunity represent …
[HTML][HTML] Immune correlates analysis of a phase 3 trial of the AZD1222 (ChAdOx1 nCoV-19) vaccine
In the phase 3 trial of the AZD1222 (ChAdOx1 nCoV-19) vaccine conducted in the US, Chile,
and Peru, anti-spike binding IgG concentration (spike IgG) and pseudovirus 50 …
and Peru, anti-spike binding IgG concentration (spike IgG) and pseudovirus 50 …