Background: Interferon-γ–release assays (IGRAs) are alternatives to the tuberculin skin test
(TST). A recent meta-analysis showed that IGRAs have high specificity, even among …

Test accuracy of interferon-γ release assays (IGRAs) for diagnosing TB differs when using
older or precommercial tools and inconsistent diagnostic criteria. This metaanalysis critically …

The last decade has witnessed significant advances in mycobacterial genomics and cellular
research which have resulted in the development of two new blood tests, the enzyme-linked …

Nontuberculous mycobacteria (NTM) are increasingly associated with pulmonary disease.
This is a worldwide phenomenon and one that is not related just to better diagnostic …

Over three previous editions, Clinical Tuberculosis has established itself as an
indispensable guide to all aspects of tuberculosis diagnosis and treatment. This fully revised …

Background. The sensitivity of whole-blood interferon-γ release assays to detect or predict
active tuberculosis in individuals infected with human immunodeficiency virus type 1 (HIV-1) …

OBJECTIVES: To compare the sensitivity and the specificity of the QuantiFERON®-TB Gold
(QFT-G) and QuantiFERON®-TB Gold In Tube (QFT-GIT) diagnostic tests for Mycobacterium …

The propensity of various nontuberculous mycobacteria to cause lung disease varies widely
and is conditioned by host factors; infection is believed to occur from environmental sources …

The hypothesis that T-cell interferon-γ responses to Mycobacterium tuberculosis-specific
antigens decline as disease activity diminishes with tuberculosis (TB) treatment has …

Background The QuantiFERON-TB-Gold Test (QFT) is more specific than the Mantoux skin-
test to discriminate between Mycobacterium tuberculosis (MTB) and non-tuberculous …