Underlying anticancer mechanisms and synergistic combinations of phytochemicals with cancer chemotherapeutics: potential benefits and risks
Cancer therapies are associated with various challenges including the emergence of
multidrug resistant tumors, toxicological issues, severe side effects, and economic burden …
multidrug resistant tumors, toxicological issues, severe side effects, and economic burden …
Catalytic Asymmetric α-Functionalization of α-Branched Aldehydes
S Vera, A Landa, A Mielgo, I Ganboa, M Oiarbide… - Molecules, 2023 - mdpi.com
Aldehydes constitute a main class of organic compounds widely applied in synthesis. As
such, catalyst-controlled enantioselective α-functionalization of aldehydes has attracted …
such, catalyst-controlled enantioselective α-functionalization of aldehydes has attracted …
Anti-Inflammatory, Analgesic and Antioxidant Potential of New (2S,3S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals and Their Corresponding Carboxylic …
In the current study, a series of new (2 S, 3 S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-
phenylbutanals (FM1-6) with their corresponding carboxylic acid analogues (FM7-12) has …
phenylbutanals (FM1-6) with their corresponding carboxylic acid analogues (FM7-12) has …
New succinimide–thiazolidinedione hybrids as multitarget antidiabetic agents: design, synthesis, bioevaluation, and molecular modelling studies
Diabetes mellitus (DM) is a metabolic disorder majorly arising from the pathophysiology of
the pancreas manifested as a decline in the insulin production or the tissue's resistance to …
the pancreas manifested as a decline in the insulin production or the tissue's resistance to …
Quantitative-HPLC-DAD polyphenols analysis, anxiolytic and cognition enhancing potentials of Sorbaria tomentosa Lindl. Rehder
Ethnopharmacological relevance Medicinal plants of the family Rosaceae have a long
history of traditional uses in the management of neurological disorders. Sorbaria tomentosa …
history of traditional uses in the management of neurological disorders. Sorbaria tomentosa …
3-(((1S,3S)-3-((R)-Hydroxy(4-(trifluoromethyl)phenyl)methyl)-4-oxocyclohexyl)methyl)pentane-2,4-dione: Design and Synthesis of New Stereopure Multi-Target …
The chiral drug candidates have more effective binding affinities for their specific protein or
receptor site for the onset of pharmacological action. Achieving all carbon stereopure …
receptor site for the onset of pharmacological action. Achieving all carbon stereopure …
Crude extract and isolated bioactive compounds from Notholirion thomsonianum (Royale) Stapf as multitargets antidiabetic agents: in-vitro and molecular docking …
Background Diabetes mellitus is a common disease effecting the lifestyles of majority world
population. In this research work, we have embarked the potential role of crude extracts and …
population. In this research work, we have embarked the potential role of crude extracts and …
Antioxidant, Enzyme Inhibitory, and Molecular Docking Approaches to the Antidiabetic Potentials of Bioactive Compounds from Persicaria hydropiper L.
Introduction. Natural products are among the most useful sources for the discovery of new
drugs against various diseases. Keeping in view the ethnobotanical relevance …
drugs against various diseases. Keeping in view the ethnobotanical relevance …
Density functional theory, molecular docking, In vitro and In vivo anti-inflammatory investigation of lapachol isolated from Fernandoa adenophylla
Medicinal plants are the main source of active chemical constituents responsible for curing
or mitigating various ailments. To discover new, safe, and effective drug candidates the …
or mitigating various ailments. To discover new, safe, and effective drug candidates the …
GC‐MS Analysis and Various In Vitro and In Vivo Pharmacological Potential of Habenaria plantaginea Lindl.
MH Mahnashi, YS Alqahtani, BA Alyami… - Evidence‐Based …, 2022 - Wiley Online Library
Background. The current study aims to give a scientific origin for employing Habenaria
plantaginea Lindl. as a potential candidate against nociception, inflammation, and pyrexia …
plantaginea Lindl. as a potential candidate against nociception, inflammation, and pyrexia …