Exposure to per-and polyfluoroalkyl substances and markers of liver injury: a systematic review and meta-analysis
Background: Experimental evidence indicates that exposure to certain pollutants is
associated with liver damage. Per-and polyfluoroalkyl substances (PFAS) are persistent …
associated with liver damage. Per-and polyfluoroalkyl substances (PFAS) are persistent …
The contribution of the exposome to the burden of cardiovascular disease
Large epidemiological and health impact assessment studies at the global scale, such as
the Global Burden of Disease project, indicate that chronic non-communicable diseases …
the Global Burden of Disease project, indicate that chronic non-communicable diseases …
[HTML][HTML] Exposure to perfluoroalkyl substances and risk of hepatocellular carcinoma in a multiethnic cohort
Background & Aims Exposure to poly-and perfluoroalkyl substances (PFAS), a class of
persistent organic pollutants, is ubiquitous. Animal studies suggest that PFAS may increase …
persistent organic pollutants, is ubiquitous. Animal studies suggest that PFAS may increase …
[HTML][HTML] PPARα/ACOX1 as a novel target for hepatic lipid metabolism disorders induced by per-and polyfluoroalkyl substances: an integrated approach
W Yang, X Ling, S He, H Cui, Z Yang, H An… - Environment …, 2023 - Elsevier
Background Per-and polyfluoroalkyl substances (PFAS) are persistent and ubiquitous
environmental contaminants with well-documented hepatotoxicity. However, the mechanistic …
environmental contaminants with well-documented hepatotoxicity. However, the mechanistic …
[HTML][HTML] Association of per-and polyfluoroalkyl substance exposure with fatty liver disease risk in US adults
Background & Aims Per-and polyfluoroalkyl substances (PFAS) are widespread pollutants
with demonstrated hepatotoxicity. Few studies have examined the association between …
with demonstrated hepatotoxicity. Few studies have examined the association between …
[HTML][HTML] Exposure to low-dose perfluorooctanoic acid promotes hepatic steatosis and disrupts the hepatic transcriptome in mice
B Attema, AWF Janssen, D Rijkers… - Molecular …, 2022 - Elsevier
Objective Perfluoroalkyl substances (PFAS) are man-made chemicals with demonstrated
endocrine-disrupting properties. Exposure to perfluorooctanoic acid (PFOA) has been linked …
endocrine-disrupting properties. Exposure to perfluorooctanoic acid (PFOA) has been linked …
Metabolic signatures of youth exposure to mixtures of per-and polyfluoroalkyl substances: a multi-cohort study
Background: Exposure to per-and polyfluoroalkyl substances (PFAS) is ubiquitous and has
been associated with an increased risk of several cardiometabolic diseases. However, the …
been associated with an increased risk of several cardiometabolic diseases. However, the …
[HTML][HTML] The exposome and liver disease-how environmental factors affect liver health
R Barouki, M Samson, EB Blanc, M Colombo… - Journal of …, 2023 - Elsevier
Since the initial development of the exposome concept, much effort has been devoted to the
characterisation of the exposome through analytical, epidemiological, and toxicological …
characterisation of the exposome through analytical, epidemiological, and toxicological …
Effects of In Utero PFOS Exposure on Epigenetics and Metabolism in Mouse Fetal Livers
Prenatal exposure to perfluorooctanesulfonate (PFOS) increases fetus' metabolic risk;
however, the investigation of the underlying mechanism is limited. In this study, pregnant …
however, the investigation of the underlying mechanism is limited. In this study, pregnant …
Effects of thiacloprid exposure on microbiota–gut–liver axis: Multiomics mechanistic analysis in Japanese quails
B Han, J Li, S Li, Y Liu, Z Zhang - Journal of Hazardous Materials, 2023 - Elsevier
Neonicotinoid insecticides (NNIs) are the most widely used class of pesticides globally.
However, NNIs may cause adverse health effects, including chronic liver disease, and …
However, NNIs may cause adverse health effects, including chronic liver disease, and …