Human papillomavirus oncoproteins: pathways to transformation

CA Moody, LA Laimins - Nature reviews cancer, 2010 - nature.com
An association between human papillomavirus (HPV) infection and the development of
cervical cancer was initially reported over 30 years ago, and today there is overwhelming …

Naphthoquinones and derivatives as potential anticancer agents: An updated review

MM Rahman, MR Islam, S Akash, S Shohag… - Chemico-Biological …, 2022 - Elsevier
One of the leading global causes of death is cancer; even though several treatment methods
have improved survival rates, the incidence and fatality rates remain high. Naphthoquinones …

Mechanisms of human papillomavirus-induced oncogenesis

K Münger, A Baldwin, KM Edwards… - Journal of …, 2004 - Am Soc Microbiol
Papillomaviruses are small nonenveloped viruses with 55-nm-diameter icosahedral capsids
that contain double-stranded DNA genomes of approximately 8,000 bp. They are widely …

A controlled trial of a human papillomavirus type 16 vaccine

LA Koutsky, KA Ault, CM Wheeler… - … England Journal of …, 2002 - Mass Medical Soc
Background Approximately 20 percent of adults become infected with human papillomavirus
type 16 (HPV-16). Although most infections are benign, some progress to anogenital cancer …

[图书][B] Human papillomaviruses

IARC Working Group on the Evaluation of … - 2007 - books.google.com
This ninetieth volume of the IARC Monographs on the Evaluation of Carcinogenic Risks to
Humansconsiders human papillomaviruses (HPVs) which were evaluated by a previous …

[HTML][HTML] Viruses associated with human cancer

ME McLaughlin-Drubin, K Munger - … Acta (BBA)-Molecular Basis of Disease, 2008 - Elsevier
It is estimated that viral infections contribute to 15–20% of all human cancers. As obligatory
intracellular parasites, viruses encode proteins that reprogram host cellular signaling …

Prevention of cervical cancer through papillomavirus vaccination

IH Frazer - Nature Reviews Immunology, 2004 - nature.com
A subset of human papillomaviruses (HPVs) promote anogenital malignancy, including
cervical cancer, and prevention and treatment strategies that reflect the causal role of HPV …

Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cells

RA DeFilippis, EC Goodwin, L Wu, D DiMaio - Journal of virology, 2003 - Am Soc Microbiol
Cervical cancer cells express high-risk human papillomavirus (HPV) E6 and E7 proteins,
and repression of HPV gene expression causes the cells to cease proliferation and undergo …

Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins

S Duensing, K Münger - International Journal of Cancer, 2004 - Wiley Online Library
Genomic instability is a hallmark of most human cancers including high‐risk human
papillomavirus (HPV)‐associated anogenital neoplasia. The two HPV‐encoded …

HPV-DNA integration and carcinogenesis: putative roles for inflammation and oxidative stress

VM Williams, M Filippova, U Soto… - Future …, 2011 - Taylor & Francis
HPV-DNA integration into cellular chromatin is usually a necessary event in the
pathogenesis of HPV-related cancer; however, the mechanism of integration has not been …