SARS-CoV-2 might directly activate NLRP3 inflammasome resulting in an endogenous
adjuvant activity necessary to mount a proper adaptive immune response against the virus …

Conspectus Carbon monoxide (CO) is a gaseous signaling molecule produced in humans
via the breakdown of heme in an O2-dependent reaction catalyzed by heme oxygenase …

Following its predecessor, the second edition of Amino Acids: Biochemistry and Nutrition
presents exhaustive coverage of amino acids in the nutrition, metabolism and health of …

Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown etiology affecting
the colon and rectum. Current therapeutics are focused on suppressing inflammation but are …

Ischemia–reperfusion (I/R) injuries are from the secondary radicals of ONOO–. Direct radical
scavenging is difficult because of their high reactivity. ONOO–is longer-lived than the …

Nature is full of examples of symbiotic relationships. The critical symbiotic relation between
host and mutualistic bacteria is attracting increasing attention to the degree that the gut …

Gaseous molecules have been increasingly explored for therapeutic development. Here,
following an analytical background introduction, a systematic review of medical gas …

Heme oxygenase-1 (HO-1) is an inducible stress protein that catalyzes the oxidative
conversion of heme to carbon monoxide (CO), iron, and biliverdin (BV), the latter of which is …

It is estimated that 10% of carbon throughout the cosmos is in the form of carbon monoxide
(CO). Earth's earliest prebiotic atmosphere included the trinity of gasotransmitters CO, nitric …

Carbon monoxide (CO) is now well recognized a pivotal endogenous signaling molecule in
mammalian lives. The proof-of-concept employing chemical carriers of exogenous CO as …